HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: S25A3 (Q00325)
Solute carrier family 25 member 3 (Phosphate carrier protein, mitochondrial) (Phosphate transport protein) (PTP)
Gene: SLC25A3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30472188, 38280479
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 504 Hs			1 362
+	Hs
		131958 WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54		S25A3_HUMAN (1-362): 5.53e-98: 296: 100.00
+	Hs
		1024470 SMUF1_HUMAN (55-504): 1.17e-109: 344: 18.62		S25A3_HUMAN (1-362): 5.53e-98: 296: 100.00
+	Hs
		1024395 HUWE1_HUMAN (76-504): 3.07e-59: 213: 10.09		S25A3_HUMAN (1-362): 5.53e-98: 296: 100.00
+	Hs
		552160 YAP1_HUMAN (51-504): 2.56e-112: 343: 100.00		ADT3_HUMAN (3-148): 1.81e-21: 94.9: 13.07
+	Hs
		131659 WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54		ADT2_HUMAN (262-359): 2.42e-11: 65.6: 16.96
+	Hs
		424996 ITCH_HUMAN (3-504): 6.65e-111: 351: 15.47		ADT2_HUMAN (262-359): 2.42e-11: 65.6: 16.96
+	Sc
		661682 TOM1_YEAST (260-504): 8.95e-40: 156: 12.10		MPCP_YEAST (47-343): 7.01e-84: 258: 39.67
+	Hs
		862435 YAP1_HUMAN (51-504): 2.56e-112: 343: 100.00		ADT4_HUMAN (249-359): 2.66e-12: 68.7: 15.20
+	Hs
		551970 YAP1_HUMAN (51-504): 2.56e-112: 343: 100.00		ADT1_HUMAN (262-359): 9.02e-12: 66.8: 17.86
+	Hs
		425044 SMUF1_HUMAN (55-504): 1.17e-109: 344: 18.62		ADT2_HUMAN (262-359): 2.42e-11: 65.6: 16.96
+	Hs
		424817 YAP1_HUMAN (51-504): 2.56e-112: 343: 100.00		ADT2_HUMAN (262-359): 2.42e-11: 65.6: 16.96
+	Hs
		552396 SMUF2_HUMAN (99-504): 3.15e-96: 309: 18.95		ADT3_HUMAN (3-148): 1.81e-21: 94.9: 13.07
+	Hs
		425039 SMUF2_HUMAN (99-504): 3.15e-96: 309: 18.95		ADT2_HUMAN (262-359): 2.42e-11: 65.6: 16.96
+	Hs
		552295 HUWE1_HUMAN (76-504): 3.07e-59: 213: 10.09		ADT3_HUMAN (3-148): 1.81e-21: 94.9: 13.07
+	Hs
		1280513 HUWE1_HUMAN (76-504): 3.07e-59: 213: 10.09		TPC_HUMAN (69-334): 7.11e-19: 87.8: 26.44
+	Hs
		1280581 HUWE1_HUMAN (76-504): 3.07e-59: 213: 10.09		S2513_HUMAN (267-357): 8.83e-16: 80.7: 20.95
+	Hs
		1429005 WWTR1_HUMAN (39-504): 6.42e-58: 199: 39.66		S2513_HUMAN (267-357): 8.83e-16: 80.7: 20.95
+	Hs
		424946 HUWE1_HUMAN (76-504): 3.07e-59: 213: 10.09		ADT2_HUMAN (262-359): 2.42e-11: 65.6: 16.96
+	Hs
		292245 WWOX_HUMAN (166-263): 7.43e-29: 120: 30.61		S2512_HUMAN (165-360): 1.13e-37: 144: 19.05
+	Hs
		1311647 KIBRA_HUMAN (169-308): 2.26e-37: 149: 27.86		ADT4_HUMAN (249-359): 2.66e-12: 68.7: 15.20