Protein: KIBRA
Protein KIBRA (HBeAg-binding protein 3) (Kidney and brain protein) (KIBRA) (WW domain-containing protein 1)

Gene: KIBRA, WWC1
Organism: Homo sapiens
Interactions: 106
UniProt ID: Q8IX03

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1051265

KPCZ
Protein kinase C zeta type

5

20

Small-scale

0.935

High

835703

KPCI
Protein kinase C iota type

3

20

Small-scale

0.839

High

862283

YAP1
Transcriptional coactivator YAP1

2

18

High-throughput

0.789

High

1152014

PTN14
Tyrosine-protein phosphatase non-receptor type 14

8

20

Small-scale

0.746

High

1230927

WWC2
Protein WWC2

1

16

Small-scale

0.713

High

1311662

WWC3
Protein WWC3

1

18

Small-scale

0.713

High

349148

LATS1
Serine/threonine-protein kinase LATS1

5

20

Small-scale

0.709

High

966586

1433G
14-3-3 protein gamma

4

20

High-throughput

0.697

High

1197008

AMOT
Angiomotin

4

20

Small-scale

0.694

High

1212193

MPP7
MAGUK p55 subfamily member 7

1

17

High-throughput

0.691

High

1311649

SAV1
Protein salvador homolog 1

1

17

High-throughput

0.691

High

1311631

ARRD1
Arrestin domain-containing protein 1

4

20

High-throughput

0.691

High

1311640

DYL2
Dynein light chain 2, cytoplasmic

4

6

High-throughput

0.691

High

1311646

PAR6B
Partitioning defective 6 homolog beta

3

14

High-throughput

0.667

High

991615

DYL1
Dynein light chain 1, cytoplasmic

3

6

High-throughput

0.662

High

1049531

1433F
14-3-3 protein eta

3

20

High-throughput

0.662

High

1311634

RHPN1
Rhophilin-1

3

20

High-throughput

0.662

High

1120628

DAG1
Dystroglycan 1

3

7

Small-scale

0.650

High

1163737

PTN21
Tyrosine-protein phosphatase non-receptor type 21

3

20

High-throughput

0.650

High

217475

E41L2
Band 4.1-like protein 2

2

17

High-throughput

0.628

High

971757

1433E
14-3-3 protein epsilon

2

12

High-throughput

0.628

High

1311660

FBW1B
F-box/WD repeat-containing protein 11

2

12

High-throughput

0.628

High

1311665

FBW1A
F-box/WD repeat-containing protein 1A

2

12

High-throughput

0.628

High

1311666

E41L3
Band 4.1-like protein 3

2

20

High-throughput

0.628

High

1311641

RHG07
Rho GTPase-activating protein 7

2

13

Small-scale

0.624

High

189687

STX7
Syntaxin-7

1

8

High-throughput

0.618

High

603304

KPCA
Protein kinase C alpha type

1

20

Small-scale

0.618

High

1091535

DLG1
Disks large homolog 1

1

17

Small-scale

0.618

High

1311628

KIBRA
Protein KIBRA

1

17

Small-scale

0.618

High

157589

CTRO
Citron Rho-interacting kinase

2

20

Small-scale

0.611

High

299769

MPDZ
Multiple PDZ domain protein

2

20

Small-scale

0.611

High

1311629

AMOL1
Angiomotin-like protein 1

2

20

Small-scale

0.611

High

1311630

PALS1
Protein PALS1

2

17

Small-scale

0.611

High

1311632

INADL
InaD-like protein

2

19

Small-scale

0.611

High

691223

1433T
14-3-3 protein theta

2

20

High-throughput

0.601

High

730037

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.601

High

1311637

US6NL
USP6 N-terminal-like protein

2

2

High-throughput

0.601

High

1311661

TNIK
TRAF2 and NCK-interacting protein kinase

2

20

High-throughput

0.590

High

1311638

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

2

18

Small-scale

0.584

High

1311652

LATS2
Serine/threonine-protein kinase LATS2

2

20

Small-scale

0.584

High

1311642

CDC5L
Cell division cycle 5-like protein

2

2

High-throughput

0.576

High

1102204

ATM
Serine-protein kinase ATM

1

10

Small-scale

0.561

High

998519

H31
Histone H3.1

1

4

Small-scale

0.536

High

159236

ABLM1
Actin-binding LIM protein 1

1

12

High-throughput

0.536

High

320570

FARP2
FERM, ARHGEF and pleckstrin domain-containing protein 2

1

11

High-throughput

0.536

High

538985

EPB41
Protein 4.1

1

18

High-throughput

0.536

High

963439

STXB1
Syntaxin-binding protein 1

1

1

High-throughput

0.536

High

1116941

AT1A4
Sodium/potassium-transporting ATPase subunit alpha-4

1

4

High-throughput

0.536

High

1292229

LONP2
Lon protease homolog 2, peroxisomal

1

6

High-throughput

0.536

High

1311633

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

6

High-throughput

0.536

High

1311644

FEM1A
Protein fem-1 homolog A

1

10

High-throughput

0.536

High

1311647

ADT4
ADP/ATP translocase 4

1

11

High-throughput

0.536

High

1311657

GCP4
Gamma-tubulin complex component 4

1

3

High-throughput

0.536

High

1311668

MYO5A
Unconventional myosin-Va

1

7

High-throughput

0.536

High

1311669

MYH4
Myosin-4

1

9

High-throughput

0.536

High

1311643

FEZ1
Fasciculation and elongation protein zeta-1

1

1

Small-scale

0.527

High

1240652

CDC73
Parafibromin

1

0

High-throughput

0.518

High

1161792

CDKN3
Cyclin-dependent kinase inhibitor 3

1

0

High-throughput

0.513

High

1273982

SSX7
Protein SSX7

1

0

High-throughput

0.513

High

1161139

MK06
Mitogen-activated protein kinase 6

1

5

High-throughput

0.508

High

508252

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

19

High-throughput

0.501

High

329848

SNX4
Sorting nexin-4

1

5

Small-scale

0.500

High

715981

CNGA1
Cyclic nucleotide-gated channel alpha-1

1

8

High-throughput

0.489

High

1311639

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

4

High-throughput

0.489

High

1311655

ATD3A
ATPase family AAA domain-containing protein 3A

1

14

High-throughput

0.489

High

1311658

FEZ2
Fasciculation and elongation protein zeta-2

1

1

Small-scale

0.481

High

123761

MYO1C
Unconventional myosin-Ic

1

16

Small-scale

0.479

High

173039

XPO1
Exportin-1

1

20

High-throughput

0.479

High

242216

PRKN
E3 ubiquitin-protein ligase parkin

1

18

High-throughput

0.479

High

417563

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.479

High

767255

MERL
Merlin

1

17

Small-scale

0.479

High

885833

KC1E
Casein kinase I isoform epsilon

1

11

Small-scale

0.479

High

891236

GSK3A
Glycogen synthase kinase-3 alpha

1

4

High-throughput

0.479

High

891667

GSK3B
Glycogen synthase kinase-3 beta

1

6

High-throughput

0.479

High

990468

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

1123706

DCTN1
Dynactin subunit 1

1

16

Small-scale

0.479

High

1272701

MAEA
E3 ubiquitin-protein transferase MAEA

1

10

Small-scale

0.479

High

1307878

ARMC8
Armadillo repeat-containing protein 8

1

6

Small-scale

0.479

High

1311636

RPGF6
Rap guanine nucleotide exchange factor 6

1

15

Small-scale

0.479

High

1311650

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

6

Small-scale

0.479

High

1311653

LIN7C
Protein lin-7 homolog C

1

20

Small-scale

0.479

High

1311659

XPO7
Exportin-7

1

15

High-throughput

0.479

High

1311663

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

10

High-throughput

0.479

High

1311667

TRRAP
Transformation/transcription domain-associated protein

1

10

High-throughput

0.479

High

1212415

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.460

High

1311654

EXOC1
Exocyst complex component 1

1

0

Small-scale

0.460

High

355639

MOC2A
Molybdopterin synthase sulfur carrier subunit

1

0

High-throughput

0.458

High

348600

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

5

High-throughput

0.457

High

1217151

RIF1
Telomere-associated protein RIF1

1

11

High-throughput

0.457

High

250696

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

20

High-throughput

0.445

High

407317

K2C6B
Keratin, type II cytoskeletal 6B

1

17

High-throughput

0.445

High

566288

K1C13
Keratin, type I cytoskeletal 13

1

20

High-throughput

0.445

High

618152

K2C4
Keratin, type II cytoskeletal 4

1

18

High-throughput

0.445

High

876490

K2C6C
Keratin, type II cytoskeletal 6C

1

17

High-throughput

0.445

High

1125360

FLNC
Filamin-C

1

15

High-throughput

0.445

High

1258498

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

8

High-throughput

0.445

High

1280844

K2C1B
Keratin, type II cytoskeletal 1b

1

18

High-throughput

0.445

High

1311635

NEK9
Serine/threonine-protein kinase Nek9

1

16

High-throughput

0.445

High

1311645

PAR6G
Partitioning defective 6 homolog gamma

1

14

High-throughput

0.445

High

1311656

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

9

High-throughput

0.445

High

1311664

UBP24
Ubiquitin carboxyl-terminal hydrolase 24

1

19

High-throughput

0.445

High

1311648

CPVL
Probable serine carboxypeptidase CPVL

1

2

Small-scale

0.437

High

354277

MOC2B
Molybdopterin synthase catalytic subunit

1

0

High-throughput

0.426

High

1311651

ENTP7
Ectonucleoside triphosphate diphosphohydrolase 7

1

0

High-throughput

0.249

Low

1309564

F219A
Protein FAM219A

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025