HitPredict

Interactor 1: ACT7 (P53492)
Actin-7 (EC 3.6.4.-) (Actin-2)
Gene: ACT7

Interactor 2: ADF6 (Q9ZSK2)
Actin-depolymerizing factor 6 (ADF-6) (AtADF6)
Gene: ADF6

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.80	0.625

Property	Details
Experiments	21798944
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 At			1 146
+	At
		862554 ACT12_ARATH (1-377): 0: 749: 95.23		ADF6_ARATH (1-146): 1.38e-65: 197: 100.00
+	At
		1280858 ACT2_ARATH (1-377): 0: 738: 92.57		ADF3_ARATH (9-146): 1.58e-59: 182: 54.35
+	Hs
		891649 ACTB_HUMAN (4-377): 0: 592: 89.84		DEST_HUMAN (12-145): 5.42e-47: 151: 30.26
+	Hs
		894665 Q1KLZ0_HUMAN (4-377): 0: 592: 89.84		DEST_HUMAN (12-145): 5.42e-47: 151: 30.26
+	Hs
		894652 ACTG_HUMAN (5-377): 0: 591: 90.08		DEST_HUMAN (12-145): 5.42e-47: 151: 30.26
+	Mm
		578583 ACTB_MOUSE (4-377): 0: 592: 89.84		COF1_MOUSE (12-145): 3.46e-46: 149: 30.07
+	Hs
		618038 ACTB_HUMAN (4-377): 0: 592: 89.84		COF1_HUMAN (12-145): 6.03e-46: 148: 30.07
+	Hs
		618096 Q1KLZ0_HUMAN (4-377): 0: 592: 89.84		COF1_HUMAN (12-145): 6.03e-46: 148: 30.07
+	Rn
		799735 ACTB_RAT (4-377): 0: 592: 89.84		COF1_RAT (12-145): 5.53e-46: 148: 30.07
+	Hs
		1092828 Q1KLZ0_HUMAN (4-377): 0: 592: 89.84		Q549N0_HUMAN (12-145): 1.38e-45: 147: 27.45
+	Hs
		618049 ACTG_HUMAN (5-377): 0: 591: 90.08		COF1_HUMAN (12-145): 6.03e-46: 148: 30.07
+	Hs
		891817 ACTB_HUMAN (4-377): 0: 592: 89.84		Q549N0_HUMAN (12-145): 1.38e-45: 147: 27.45
+	Hs
		892124 ACTB_HUMAN (4-377): 0: 592: 89.84		COF2_HUMAN (12-145): 1.38e-45: 147: 27.45
+	Hs
		929891 ACTG_HUMAN (5-377): 0: 591: 90.08		Q549N0_HUMAN (12-145): 1.38e-45: 147: 27.45
+	Hs
		891728 ACTB_HUMAN (4-377): 0: 592: 89.84		TWF1_HUMAN (13-145): 1.96e-36: 129: 25.71
+	Hs
		929835 ACTG_HUMAN (5-377): 0: 591: 90.08		TWF1_HUMAN (13-145): 1.96e-36: 129: 25.71
+	Hs
		891650 ACTB_HUMAN (4-377): 0: 592: 89.84		GMFB_HUMAN (17-145): 7.88e-38: 127: 21.81
+	Hs
		894697 ACTG_HUMAN (5-377): 0: 591: 90.08		GMFB_HUMAN (17-145): 7.88e-38: 127: 21.81
+	Ce
		501473 ACT4_CAEEL (4-377): 0: 593: 88.77		ADF1_CAEEL (12-142): 5.76e-31: 111: 29.22
+	Hs
		891834 ACTB_HUMAN (4-377): 0: 592: 89.84		TWF2_HUMAN (19-146): 2.45e-11: 61.9: 18.66