Interactor 1: RPGP1 (P47736)
Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1)
Gene: RAP1GAP
Interactor 2: RPGP2 (Q684P5)
Rap1 GTPase-activating protein 2 (Rap1GAP2) (GTPase-activating Rap/Ran-GAP domain-like protein 4)
Gene: RAP1GAP2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Rap-GAP_dimer~Rap-GAP_dimer, Rap-GAP_dimer~Rap_GAP |
| Common GO terms | GO:0002250 - adaptive immune response GO:0005096 - GTPase activator activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051056 - regulation of small GTPase mediated signal transduction |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
