HitPredict

Interactor 1: UBP14 (P54578)
Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14)
Gene: USP14

Interactor 2: PAAF1 (Q9BRP4)
Proteasomal ATPase-associated factor 1 (Protein G-16) (WD repeat-containing protein 71)
Gene: PAAF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30425250
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UCH~WD40
Common GO terms	GO:0000502 - proteasome complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 392
+	Hs
		870906 UBP14_HUMAN (1-494): 7.04e-147: 431: 100.00		GBB4_HUMAN (65-350): 1.54e-68: 221: 22.64
+	Hs
		863385 UBP14_HUMAN (1-494): 7.04e-147: 431: 100.00		COPA_HUMAN (4-376): 1.15e-43: 164: 12.85
+	Hs
		870739 UBP14_HUMAN (1-494): 7.04e-147: 431: 100.00		GBB1_HUMAN (6-283): 1.85e-46: 164: 19.66
+	Hs
		870778 UBP14_HUMAN (1-494): 7.04e-147: 431: 100.00		TBL3_HUMAN (86-268): 2.46e-18: 89: 28.50
+	Hs
		870866 UBP14_HUMAN (1-494): 7.04e-147: 431: 100.00		SNR40_HUMAN (308-388): 1.67e-09: 60.6: 11.63
+	Hs
		1281441 UBP36_HUMAN (65-482): 3.73e-90: 299: 17.54		FBXW7_HUMAN (167-390): 5.39e-51: 183: 14.98
+	Hs
		271161 UBP2_HUMAN (56-487): 5.71e-90: 288: 16.30		FBXW7_HUMAN (167-390): 5.39e-51: 183: 14.98
+	Hs
		209481 UBP42_HUMAN (59-482): 3.47e-89: 299: 17.37		PLRG1_HUMAN (269-390): 2.01e-20: 94.9: 14.84
+	Sc
		797700 UBP6_YEAST (4-481): 1.15e-88: 282: 30.10		RPN14_YEAST (111-340): 7.56e-26: 109: 30.49
+	Hs
		1346960 UBP36_HUMAN (65-482): 3.73e-90: 299: 17.54		NLE1_HUMAN (305-390): 1.26e-18: 89.4: 15.56
+	Hs
		1016340 UBP36_HUMAN (65-482): 3.73e-90: 299: 17.54		TBL3_HUMAN (86-268): 2.46e-18: 89: 28.50
+	Hs
		903571 UBP36_HUMAN (65-482): 3.73e-90: 299: 17.54		WDR5_HUMAN (314-390): 8.57e-15: 76.6: 9.88
+	Hs
		64195 UBP27_HUMAN (35-494): 3.18e-94: 294: 18.41		TAF5L_HUMAN (91-235): 1.05e-11: 68.2: 26.21
+	Hs
		1288312 UBP42_HUMAN (59-482): 3.47e-89: 299: 17.37		SNR40_HUMAN (308-388): 1.67e-09: 60.6: 11.63
+	Hs
		1288358 UBP36_HUMAN (65-482): 3.73e-90: 299: 17.54		SNR40_HUMAN (308-388): 1.67e-09: 60.6: 11.63
+	Hs
		267805 UBP22_HUMAN (66-487): 1.12e-91: 290: 19.03		TAF5L_HUMAN (91-235): 1.05e-11: 68.2: 26.21
+	Hs
		267775 UBP51_HUMAN (35-486): 3.31e-86: 281: 18.26		TAF5L_HUMAN (91-235): 1.05e-11: 68.2: 26.21
+	Sc
		744649 UBP8_YEAST (105-485): 5.83e-38: 146: 20.51		TAF5_YEAST (126-391): 8.85e-57: 200: 17.59
+	Sc
		837445 UBP8_YEAST (105-485): 5.83e-38: 146: 20.51		COPA_YEAST (3-376): 1.92e-44: 166: 10.58