HitPredict

Interactor 1: EPHA5 (P54756)
Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)
Gene: EPHA5

Interactor 2: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1037 Hs			1 340
+	Hs
		665388 EPHA3_HUMAN (51-1037): 0: 1232: 66.53		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		920973 EPHA7_HUMAN (37-1035): 0: 1222: 62.69		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		665199 EPHA2_HUMAN (58-1037): 0: 1105: 50.86		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Rn
		192655 INSR_RAT (400-940): 1.09e-142: 464: 29.88		GBB4_RAT (1-340): 1.71e-98: 296: 90.00
+	Hs
		674357 UFO_HUMAN (290-1017): 4.06e-147: 463: 21.89		LIS1_HUMAN (259-340): 1.35e-18: 87.8: 23.17
+	Hs
		609202 FGFR3_HUMAN (404-988): 2.12e-147: 461: 21.80		LIS1_HUMAN (259-340): 1.35e-18: 87.8: 23.17
+	Hs
		789108 FRK_HUMAN (669-941): 1.17e-65: 232: 42.18		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		412122 FYN_HUMAN (669-933): 3.12e-64: 229: 44.20		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		412300 FYN_HUMAN (669-933): 3.12e-64: 229: 44.20		SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30
+	Hs
		196966 FRK_HUMAN (669-941): 1.17e-65: 232: 42.18		PRP4_HUMAN (51-253): 1.06e-12: 70.5: 25.85
+	Hs
		196942 LYN_HUMAN (659-933): 1.73e-65: 231: 43.68		PRP4_HUMAN (51-253): 1.06e-12: 70.5: 25.85