Protein: SPDEF
SAM pointed domain-containing Ets transcription factor (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets) (Prostate-derived Ets factor)

Gene: SPDEF
Organism: Homo sapiens
Interactions: 35
UniProt ID: O95238

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0002068 - glandular epithelial cell development
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

309245

MECOM
Histone-lysine N-methyltransferase MECOM

3

2

High-throughput

0.667

High

309263

PRD16
Histone-lysine N-methyltransferase PRDM16

3

2

High-throughput

0.667

High

309260

NKX31
Homeobox protein Nkx-3.1

2

20

Small-scale

0.619

High

309246

U119A
Protein unc-119 homolog A

3

1

High-throughput

0.609

High

309265

MYO5C
Unconventional myosin-Vc

3

2

High-throughput

0.609

High

309251

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

2

0

High-throughput

0.585

High

309242

PSA1
Proteasome subunit alpha type-1

2

0

High-throughput

0.580

High

309253

CEP57
Centrosomal protein of 57 kDa

2

0

High-throughput

0.580

High

309268

CD11A
Cyclin-dependent kinase 11A

1

3

Small-scale

0.578

High

309266

ANM8
Protein arginine N-methyltransferase 8

2

1

High-throughput

0.574

High

309252

SNX20
Sorting nexin-20

2

1

High-throughput

0.553

High

309243

PCGF2
Polycomb group RING finger protein 2

1

12

High-throughput

0.541

High

309239

ANDR
Androgen receptor

1

15

Small-scale

0.501

High

309244

SRPK2
SRSF protein kinase 2

1

1

High-throughput

0.501

High

63158

U119B
Protein unc-119 homolog B

1

1

High-throughput

0.489

High

309267

KLHL9
Kelch-like protein 9

1

4

High-throughput

0.489

High

309248

STK11
Serine/threonine-protein kinase STK11

1

1

Small-scale

0.481

High

209557

PRC1
Protein regulator of cytokinesis 1

1

2

High-throughput

0.479

High

309241

CD11B
Cyclin-dependent kinase 11B

1

3

Small-scale

0.479

High

309256

ESR2
Estrogen receptor beta

1

15

High-throughput

0.479

High

122422

MEN1
Menin

1

0

High-throughput

0.458

High

309247

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

309254

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

309262

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

309238

B3A2
Anion exchange protein 2

3

0

High-throughput

0.347

High

309249

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

3

0

High-throughput

0.347

High

309257

MACIR
Macrophage immunometabolism regulator

3

0

High-throughput

0.347

High

309240

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

2

0

High-throughput

0.316

High

309250

TTC23
Tetratricopeptide repeat protein 23

2

0

High-throughput

0.316

High

309258

F161B
Protein FAM161B

2

0

High-throughput

0.316

High

309261

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.316

High

152123

STX16
Syntaxin-16

1

0

High-throughput

0.269

Low

309259

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.269

Low

309255

BRK1
Protein BRICK1

1

0

High-throughput

0.268

Low

309264

ANLN
Anillin

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024