HitPredict

Interactor 1: H33A (C0HL66)
Histone H3.3A (H3.A)
Gene: His3.3A

Interactor 2: ASF1 (Q9V464)
Histone chaperone asf1 (Anti-silencing function protein 1) (Replication-coupling assembly factor subunit ASF1) (RCAF subunit ASF1) (dASF1)
Gene: ASF1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.53	1.00	0.730

Property	Details
Experiments	19079254, 14605208
Identification Methods	two hybrid array, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ASF1_hist_chap~Histone
Common GO terms	GO:0005634 - nucleus GO:0005700 - polytene chromosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 136 Dm			1 218
+	Dm
		381720 H3_DROME (1-136): 5.34e-59: 180: 97.06		ASF1_DROME (1-218): 1.06e-132: 373: 100.00
+	Hs
		998963 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		ASF1A_HUMAN (1-181): 1.19e-97: 284: 65.19
+	Mm
		999035 H31_MOUSE (1-136): 3.09e-60: 183: 96.32		ASF1A_MOUSE (1-181): 1.36e-97: 284: 65.19
+	Hs
		1017314 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		ASF1A_HUMAN (1-181): 1.19e-97: 284: 65.19
+	Mm
		1017372 H33_MOUSE (1-136): 1.13e-59: 182: 100.00		ASF1A_MOUSE (1-181): 1.36e-97: 284: 65.19
+	Gg
		1017386 H33_CHICK (1-136): 1.13e-59: 182: 100.00		ASF1_CHICK (1-181): 1.19e-97: 284: 65.19
+	Hs
		998868 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		ASF1B_HUMAN (1-154): 3.52e-97: 283: 71.43
+	Hs
		1017251 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		ASF1B_HUMAN (1-154): 3.52e-97: 283: 71.43
+	Hs
		1162086 H31T_HUMAN (1-136): 2.59e-59: 181: 93.38		ASF1A_HUMAN (1-181): 1.19e-97: 284: 65.19
+	Mm
		1016768 H32_MOUSE (1-136): 5.34e-59: 180: 97.06		ASF1A_MOUSE (1-181): 1.36e-97: 284: 65.19
+	Gg
		1016774 H32_CHICK (1-136): 5.34e-59: 180: 97.06		ASF1_CHICK (1-181): 1.19e-97: 284: 65.19
+	Hs
		1162057 H31T_HUMAN (1-136): 2.59e-59: 181: 93.38		ASF1B_HUMAN (1-154): 3.52e-97: 283: 71.43
+	Hs
		1258986 H32_HUMAN (1-136): 5.34e-59: 180: 97.06		ASF1A_HUMAN (1-181): 1.19e-97: 284: 65.19
+	Mm
		999037 H31_MOUSE (1-136): 3.09e-60: 183: 96.32		ASF1B_MOUSE (1-171): 4.16e-95: 277: 65.50
+	Mm
		1017376 H33_MOUSE (1-136): 1.13e-59: 182: 100.00		ASF1B_MOUSE (1-171): 4.16e-95: 277: 65.50
+	Mm
		1016770 H32_MOUSE (1-136): 5.34e-59: 180: 97.06		ASF1B_MOUSE (1-171): 4.16e-95: 277: 65.50
+	Hs
		883710 CENPA_HUMAN (9-133): 2.43e-45: 146: 50.76		ASF1B_HUMAN (1-154): 3.52e-97: 283: 71.43
+	Sc
		736700 H3_YEAST (1-136): 3.63e-54: 168: 90.44		ASF1_YEAST (1-156): 1.22e-86: 259: 58.33
+	Sp
		267799 H31_SCHPO (1-136): 1.12e-57: 177: 91.91		ASF1_SCHPO (1-154): 5.79e-82: 246: 52.50