Protein: ASF1B
Histone chaperone ASF1B (Anti-silencing function protein 1 homolog B) (hAsf1) (hAsf1b) (CCG1-interacting factor A-II) (CIA-II) (hCIA-II)

Gene: ASF1B
Organism: Homo sapiens
Interactions: 74
UniProt ID: Q9NVP2

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0001835 - blastocyst hatching
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

998868

H31
Histone H3.1

17

19

Small-scale

0.985

High

1017251

H33
Histone H3.3

7

19

Small-scale

0.965

High

888350

MCM2
DNA replication licensing factor MCM2

7

11

Small-scale

0.964

High

980423

H4
Histone H4

5

5

Small-scale

0.935

High

881104

NASP
Nuclear autoantigenic sperm protein

5

2

High-throughput

0.930

High

1450753

ASF1A
Histone chaperone ASF1A

4

1

Small-scale

0.895

High

1162057

H31T
Histone H3.1t

3

19

Small-scale

0.847

High

1094819

CAF1B
Chromatin assembly factor 1 subunit B

8

14

Small-scale

0.755

High

1288383

TLK2
Serine/threonine-protein kinase tousled-like 2

8

6

Small-scale

0.752

High

1094742

CAF1A
Chromatin assembly factor 1 subunit A

7

5

Small-scale

0.747

High

1311323

CDAN1
Codanin-1

6

4

Small-scale

0.741

High

926690

HIRA
Protein HIRA

6

17

Small-scale

0.740

High

1159026

RBBP7
Histone-binding protein RBBP7

6

5

Small-scale

0.736

High

1392828

TONSL
Tonsoku-like protein

6

1

Small-scale

0.734

High

1066519

RBBP4
Histone-binding protein RBBP4

5

5

High-throughput

0.718

High

1450750

TLK1
Serine/threonine-protein kinase tousled-like 1

5

7

Small-scale

0.718

High

168333

HAT1
Histone acetyltransferase type B catalytic subunit

5

2

Small-scale

0.716

High

1253828

MMS22
Protein MMS22-like

5

1

Small-scale

0.714

High

1450755

CDIN1
CDAN1-interacting nuclease 1

5

2

High-throughput

0.714

High

1128294

MCM6
DNA replication licensing factor MCM6

5

11

Small-scale

0.714

High

1353375

IPO4
Importin-4

4

3

Small-scale

0.697

High

1446357

UBN1
Ubinuclein-1

4

5

High-throughput

0.697

High

1450756

CABIN
Calcineurin-binding protein cabin-1

4

3

High-throughput

0.697

High

1256487

UBN2
Ubinuclein-2

3

6

High-throughput

0.675

High

755802

MCM4
DNA replication licensing factor MCM4

3

10

High-throughput

0.667

High

756372

MCM7
DNA replication licensing factor MCM7

3

10

High-throughput

0.667

High

1197573

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

3

1

High-throughput

0.662

High

1201701

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

3

1

High-throughput

0.662

High

1217211

RIF1
Telomere-associated protein RIF1

3

4

High-throughput

0.662

High

883710

CENPA
Histone H3-like centromeric protein A

1

19

High-throughput

0.618

High

1450749

BAZ1B
Tyrosine-protein kinase BAZ1B

1

5

High-throughput

0.575

High

1450751

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

7

High-throughput

0.575

High

1341196

PPTC7
Protein phosphatase PTC7 homolog

2

1

High-throughput

0.574

High

905495

HCFC1
Host cell factor 1

1

1

Small-scale

0.552

High

1245817

ATAD2
ATPase family AAA domain-containing protein 2

1

0

High-throughput

0.546

High

370368

CYTA
Cystatin-A

1

1

High-throughput

0.536

High

1030500

FABP5
Fatty acid-binding protein 5

1

1

High-throughput

0.536

High

1415950

HIRP3
HIRA-interacting protein 3

1

1

High-throughput

0.536

High

907293

STA5B
Signal transducer and activator of transcription 5B

1

0

High-throughput

0.513

High

249788

DOK2
Docking protein 2

1

0

High-throughput

0.493

High

959993

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.493

High

985029

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.493

High

991732

DYL1
Dynein light chain 1, cytoplasmic

1

0

High-throughput

0.493

High

1005430

SERB
Phosphoserine phosphatase

1

0

High-throughput

0.493

High

1046427

UBXN1
UBX domain-containing protein 1

1

0

High-throughput

0.493

High

1361922

TITIN
Titin

1

0

High-throughput

0.493

High

670022

MCM3
DNA replication licensing factor MCM3

1

11

High-throughput

0.479

High

675179

TNR6
Tumor necrosis factor receptor superfamily member 6

1

1

High-throughput

0.479

High

756069

MCM5
DNA replication licensing factor MCM5

1

11

High-throughput

0.479

High

942918

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

3

High-throughput

0.479

High

1045826

TF65
Transcription factor p65

1

1

High-throughput

0.479

High

1138097

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

1338994

NUP43
Nucleoporin Nup43

1

7

High-throughput

0.479

High

1368333

DPF3
Zinc finger protein DPF3

1

4

Small-scale

0.479

High

1387592

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

2

High-throughput

0.479

High

1450752

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

369925

CO3
Complement C3

1

0

High-throughput

0.458

High

1313468

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1411729

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

1415881

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

909396

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

1

High-throughput

0.457

High

993773

UBC9
SUMO-conjugating enzyme UBC9

1

2

High-throughput

0.457

High

243749

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

11

High-throughput

0.445

High

1402784

STRBP
Spermatid perinuclear RNA-binding protein

1

5

High-throughput

0.445

High

1437359

LN28A
Protein lin-28 homolog A

1

1

High-throughput

0.445

High

229577

NRDC
Nardilysin

1

0

High-throughput

0.426

High

1436046

DCR1B
5' exonuclease Apollo

1

0

High-throughput

0.426

High

1450748

RHG23
Rho GTPase-activating protein 23

1

0

High-throughput

0.426

High

767533

RECO
Recoverin

2

0

High-throughput

0.328

High

1010725

DCD
Dermcidin

1

0

High-throughput

0.279

Low

1450754

RT07
Small ribosomal subunit protein uS7m

1

0

High-throughput

0.269

Low

519248

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

402425

GBA1
Lysosomal acid glucosylceramidase

1

0

High-throughput

0.232

Low

1410881

MGME1
Mitochondrial genome maintenance exonuclease 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025