Interactor 1: ORC1 (P54784)
Origin recognition complex subunit 1 (Origin recognition complex 120 kDa subunit)
Gene: ORC1

Interactor 2: ORC4 (P54791)
Origin recognition complex subunit 4 (Origin recognition complex 56 kDa subunit)
Gene: ORC4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 9001208, 18647841, 11805826, 28191893, 17880717, 17825065, 35217664, 22421151, 12110181, 7585959, 26456755, 16554755, 16429126, 32826290, 19896182, 37968396, 20595233
Identification Methods coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification, pull down, affinity chromatography technology, two hybrid, biochemical, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~ORC4_C, AAA_lid_10~ORC4_C
Common GO terms GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005656 - nuclear pre-replicative complex
GO:0005664 - nuclear origin of replication recognition complex
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 914
Sc

1 529
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Sp
+ Sp
+ Dm
+ Sp
+ Sp
+ Sp
+ At

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Last updated: 15 Jul 2024