HitPredict

Interactor 1: TERA1 (P54811)
Transitional endoplasmic reticulum ATPase homolog 1 (EC 3.6.4.6) (Cell division cycle-related protein 48.1) (p97/CDC48 homolog 1)
Gene: cdc-48.1

Interactor 2: TERA2 (P54812)
Transitional endoplasmic reticulum ATPase homolog 2 (EC 3.6.4.6) (Cell division cycle-related protein 48.2) (p97/CDC48 homolog 2)
Gene: cdc-48.2

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.940

The method score is based on:

Property Details
Experiments 17369820, 25721663, 16647269, 18692475, 19123269, unassigned701
Identification Methods two hybrid, affinity chromatography technology, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~CDC48_2, AAA~CDC48_N, AAA~Vps4_C, AAA_lid_3~AAA_lid_3, AAA_lid_3~CDC48_2, AAA_lid_3~CDC48_N, AAA_lid_3~Vps4_C, CDC48_2~CDC48_2, CDC48_2~CDC48_N, CDC48_N~CDC48_N, Vps4_C~Vps4_C
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0009792 - embryo development ending in birth or egg hatching
GO:0016887 - ATP hydrolysis activity
and 6 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 809
Ce

1 810
+ Dm
+ Ce
+ Ce
+ At
+ Rn
+ Hs
+ Mm
+ Sc
+ Hs
+ Sp
+ Sp
+ Sc
+ Hs
+ At
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024