HitPredict

Interactor 1: RAC2 (P48554)
Ras-related protein Rac2
Gene: RAC2

Interactor 2: SPRI (Q8MQW8)
Protein sprint (SH2 poly-proline-containing Ras-interactor protein)
Gene: SPRI

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RA~Ras, Ras~VPS9
Common GO terms	GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Dm			1 1789
+	Dm
		828005 RAC1_DROME (1-192): 9.45e-82: 242: 93.23		SPRI_DROME (1-1789): 0: 1502: 100.00
+	Ce
		110101 RAC1_CAEEL (1-192): 7.45e-83: 245: 79.69		G5EBS9_CAEEL (1292-1786): 6.91e-134: 444: 27.30
+	Hs
		557206 RAC1_HUMAN (1-192): 1.58e-84: 249: 89.58		SRC_HUMAN (330-574): 8.22e-56: 206: 16.86
+	Hs
		440481 RAC1_HUMAN (1-192): 1.58e-84: 249: 89.58		FYN_HUMAN (318-575): 3.28e-55: 204: 17.42
+	Hs
		76673 B4E1U9_HUMAN (1-192): 1.77e-85: 253: 54.85		RIN3_HUMAN (458-969): 1.85e-49: 194: 20.19
+	Hs
		440334 RAC2_HUMAN (1-192): 2.98e-81: 241: 88.02		FYN_HUMAN (318-575): 3.28e-55: 204: 17.42
+	Hs
		440471 CDC42_HUMAN (1-192): 1.93e-77: 231: 67.71		FYN_HUMAN (318-575): 3.28e-55: 204: 17.42
+	Hs
		462976 RHOQ_HUMAN (4-179): 1.12e-84: 250: 66.48		YES_HUMAN (337-574): 2.32e-48: 184: 15.45
+	Hs
		463050 RAC1_HUMAN (1-192): 1.58e-84: 249: 89.58		YES_HUMAN (337-574): 2.32e-48: 184: 15.45
+	Hs
		462971 RAC2_HUMAN (1-192): 2.98e-81: 241: 88.02		YES_HUMAN (337-574): 2.32e-48: 184: 15.45
+	Hs
		463224 RHOJ_HUMAN (2-190): 3.74e-79: 236: 59.79		YES_HUMAN (337-574): 2.32e-48: 184: 15.45
+	Hs
		463059 RHOG_HUMAN (1-192): 2.36e-78: 233: 67.71		YES_HUMAN (337-574): 2.32e-48: 184: 15.45
+	Hs
		601329 RHOQ_HUMAN (4-179): 1.12e-84: 250: 66.48		TENS3_HUMAN (453-605): 1.03e-32: 141: 20.33
+	Hs
		988441 RAC1_HUMAN (1-192): 1.58e-84: 249: 89.58		TENS3_HUMAN (453-605): 1.03e-32: 141: 20.33
+	Hs
		581111 RAC2_HUMAN (1-192): 2.98e-81: 241: 88.02		TENS3_HUMAN (453-605): 1.03e-32: 141: 20.33
+	Hs
		319060 RAC1_HUMAN (1-192): 1.58e-84: 249: 89.58		K0754_HUMAN (560-1141): 3.58e-25: 116: 15.63
+	Ce
		110770 RAC1_CAEEL (1-192): 7.45e-83: 245: 79.69		G5ECF0_CAEEL (333-646): 4.62e-24: 113: 22.74
+	Hs
		319049 RAC2_HUMAN (1-192): 2.98e-81: 241: 88.02		K0754_HUMAN (560-1141): 3.58e-25: 116: 15.63
+	Hs
		319077 RHOJ_HUMAN (2-190): 3.74e-79: 236: 59.79		K0754_HUMAN (560-1141): 3.58e-25: 116: 15.63
+	Hs
		319064 RHOG_HUMAN (1-192): 2.36e-78: 233: 67.71		K0754_HUMAN (560-1141): 3.58e-25: 116: 15.63