HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: LRFN1 (Q9P244)
Leucine-rich repeat and fibronectin type III domain-containing protein 1 (Synaptic adhesion-like molecule 2)
Gene: LRFN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1824 Hs			1 771
+	Hs
		1343626 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		LRFN1_HUMAN (1-771): 1.42e-157: 478: 100.00
+	Hs
		231747 KIF1B_HUMAN (191-589): 6.21e-42: 171: 15.66		LRFN1_HUMAN (1-771): 1.42e-157: 478: 100.00
+	Mm
		1103492 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		LRFN1_MOUSE (1-771): 3.23e-149: 456: 95.21
+	Hs
		1020230 PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14		LRFN1_HUMAN (1-771): 1.42e-157: 478: 100.00
+	Hs
		1295221 RADIL_HUMAN (830-1106): 4.06e-27: 122: 18.06		FLRT1_HUMAN (13-613): 9.72e-68: 238: 19.84
+	Mm
		1194737 LNX2_MOUSE (973-1126): 6.83e-17: 88.9: 20.38		AMGO1_MOUSE (33-387): 1.38e-74: 252: 25.00
+	Rn
		1115126 PARD3_RAT (937-1811): 3.83e-18: 93.7: 12.90		LRRC4_RAT (30-480): 1.53e-60: 218: 22.59
+	Mm
		1207544 DLG2_MOUSE (936-1143): 2.99e-34: 145: 24.55		LRC4C_MOUSE (5-333): 5.09e-25: 112: 14.76
+	Hs
		1050029 SCRIB_HUMAN (989-1133): 4.27e-22: 106: 26.85		LRIG1_HUMAN (2-261): 4.49e-34: 142: 20.56
+	Hs
		1162244 GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72		LRFN4_HUMAN (2-109): 1.48e-16: 85.9: 17.12
+	Mm
		471547 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		LRC4B_MOUSE (2-161): 1.65e-25: 114: 17.84
+	Mm
		1143410 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		LRC4C_MOUSE (5-333): 5.09e-25: 112: 14.76
+	Mm
		1143377 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		LRFN4_MOUSE (2-109): 2.66e-16: 85.1: 18.02
+	Rn
		677783 DLG4_RAT (1002-1238): 9.23e-28: 123: 17.51		LRFN2_RAT (2-109): 1.59e-14: 79.7: 13.51
+	Mm
		1143368 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		LRFN2_MOUSE (2-109): 2.06e-14: 79.3: 13.51
+	Mm
		936185 DLG3_MOUSE (1010-1232): 6.69e-13: 76: 19.69		LRC4C_MOUSE (5-333): 5.09e-25: 112: 14.76
+	Hs
		1020181 PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14		LRFN4_HUMAN (2-109): 1.48e-16: 85.9: 17.12
+	Hs
		280046 MPDZ_HUMAN (971-1166): 2.25e-13: 78.3: 21.43		LRFN4_HUMAN (2-109): 1.48e-16: 85.9: 17.12
+	Rn
		1115172 DLG3_RAT (1010-1232): 3.36e-13: 77.2: 20.08		LRFN2_RAT (2-109): 1.59e-14: 79.7: 13.51
+	Mm
		936183 DLG3_MOUSE (1010-1232): 6.69e-13: 76: 19.69		LRFN2_MOUSE (2-109): 2.06e-14: 79.3: 13.51