Interactor 1: KMT2A (P55200)
Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]
Gene: KMT2A
Interactor 2: LDB1 (P70662)
LIM domain-binding protein 1 (LDB-1) (Carboxyl-terminal LIM domain-binding protein 2) (CLIM-2) (LIM domain-binding factor CLIM2) (mLdb1) (Nuclear LIM interactor)
Gene: LDB1
Species: Mus musculus
Source: innatedb
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 0.55 | 0.458 |
The method score is based on:
Property | Details |
---|---|
Experiments | 21186366 |
Identification Methods | anti tag coimmunoprecipitation |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0042803 - protein homodimerization activity GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0140297 - DNA-binding transcription factor binding |
Homologous interactions | 0 |
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Last updated: 15 Jul 2024