HitPredict

Interactor 1: FOXG1 (P55316)
Forkhead box protein G1 (Brain factor 1) (BF-1) (BF1) (Brain factor 2) (BF-2) (BF2) (hBF-2) (Forkhead box protein G1A) (Forkhead box protein G1B) (Forkhead box protein G1C) (Forkhead-related protein FKHL1) (HFK1) (Forkhead-related protein FKHL2) (HFK2) (Forkhead-related protein FKHL3) (HFK3)
Gene: FOXG1

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19683680
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 489 Hs			1 522
+	Hs
		1016159 FOXO1_HUMAN (60-474): 2.23e-51: 186: 22.90		TRAF3_HUMAN (19-501): 9.91e-86: 277: 22.18
+	Hs
		877729 FOXA1_HUMAN (80-448): 8.86e-50: 178: 22.84		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		536858 FX4L6_HUMAN (75-339): 1.98e-50: 179: 30.86		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		537016 FOXC2_HUMAN (115-470): 1.92e-49: 178: 27.94		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		1016232 FOXO1_HUMAN (60-474): 2.23e-51: 186: 22.90		TRI47_HUMAN (67-316): 1.02e-36: 145: 17.84
+	Hs
		537014 FOXB1_HUMAN (169-452): 7.39e-48: 169: 27.82		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90