Protein: SL9A4
Sodium/hydrogen exchanger 4 (Na(+)/H(+) exchanger 4) (NHE-4) (Solute carrier family 9 member 4)

Gene: SL9A4, SLC9A4
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q6AI14

Gene Ontology (top 5):
GO:0001696 - gastric acid secretion
GO:0002068 - glandular epithelial cell development
GO:0005886 - plasma membrane
GO:0006811 - monoatomic ion transport
GO:0015385 - sodium:proton antiporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1230839

CHP1
Calcineurin B homologous protein 1

2

20

Small-scale

0.755

High

225748

CHP2
Calcineurin B homologous protein 2

1

20

Small-scale

0.647

High

61114

T131L
Transmembrane protein 131-like

1

6

High-throughput

0.445

High

243804

ADCY3
Adenylate cyclase type 3

1

3

High-throughput

0.445

High

321266

ERLN2
Erlin-2

1

5

High-throughput

0.445

High

342915

HERC2
E3 ubiquitin-protein ligase HERC2

1

4

High-throughput

0.445

High

761425

HS71L
Heat shock 70 kDa protein 1-like

1

4

High-throughput

0.445

High

1230832

SORL
Sortilin-related receptor

1

6

High-throughput

0.445

High

1230834

ASTRA
Protein Aster-A

1

7

High-throughput

0.445

High

1230840

RNF5
E3 ubiquitin-protein ligase RNF5

1

4

High-throughput

0.445

High

1230841

ESYT1
Extended synaptotagmin-1

1

5

High-throughput

0.445

High

1230843

VEZA
Vezatin

1

2

High-throughput

0.445

High

1230844

CNNM1
Metal transporter CNNM1

1

1

High-throughput

0.445

High

1143720

PON2
Serum paraoxonase/arylesterase 2

1

0

High-throughput

0.426

High

68017

P121C
Nuclear envelope pore membrane protein POM 121C

1

1

High-throughput

0.407

High

283277

ERLN1
Erlin-1

1

4

High-throughput

0.407

High

291382

NU155
Nuclear pore complex protein Nup155

1

2

High-throughput

0.407

High

343968

HS74L
Heat shock 70 kDa protein 4L

1

11

High-throughput

0.407

High

347108

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.407

High

531087

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

6

High-throughput

0.407

High

617310

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

4

High-throughput

0.407

High

679189

DNJB1
DnaJ homolog subfamily B member 1

1

6

High-throughput

0.407

High

761713

HSP74
Heat shock 70 kDa protein 4

1

11

High-throughput

0.407

High

844258

MTHR
Methylenetetrahydrofolate reductase

1

3

High-throughput

0.407

High

894814

EMD
Emerin

1

2

High-throughput

0.407

High

944270

TMM33
Transmembrane protein 33

1

3

High-throughput

0.407

High

1010479

EREP3
Protein ENTREP3

1

2

High-throughput

0.407

High

1085438

SRBP2
Sterol regulatory element-binding protein 2

1

4

High-throughput

0.407

High

1103546

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

1

3

High-throughput

0.407

High

1105479

OS9
Protein OS-9

1

2

High-throughput

0.407

High

1131470

MBTP1
Membrane-bound transcription factor site-1 protease

1

1

High-throughput

0.407

High

1211069

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

3

High-throughput

0.407

High

1230818

RETST
All-trans-retinol 13,14-reductase

1

2

High-throughput

0.407

High

1230819

ABH15
Protein ABHD15

1

2

High-throughput

0.407

High

1230820

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

6

High-throughput

0.407

High

1230821

VRK2
Serine/threonine-protein kinase VRK2

1

5

High-throughput

0.407

High

1230822

PLPL6
Patatin-like phospholipase domain-containing protein 6

1

6

High-throughput

0.407

High

1230823

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

1

1

High-throughput

0.407

High

1230824

EMC1
ER membrane protein complex subunit 1

1

3

High-throughput

0.407

High

1230825

LEMD2
LEM domain-containing protein 2

1

2

High-throughput

0.407

High

1230826

B3GL2
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2

1

2

High-throughput

0.407

High

1230827

PDZD8
PDZ domain-containing protein 8

1

3

High-throughput

0.407

High

1230828

DJB14
DnaJ homolog subfamily B member 14

1

14

High-throughput

0.407

High

1230829

THEM6
Protein THEM6

1

1

High-throughput

0.407

High

1230830

TM131
Transmembrane protein 131

1

6

High-throughput

0.407

High

1230831

HS105
Heat shock protein 105 kDa

1

11

High-throughput

0.407

High

1230833

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

6

High-throughput

0.407

High

1230835

FAF2
FAS-associated factor 2

1

1

High-throughput

0.407

High

1230837

ERLEC
Endoplasmic reticulum lectin 1

1

2

High-throughput

0.407

High

1230838

DNJC7
DnaJ homolog subfamily C member 7

1

5

High-throughput

0.407

High

1230842

DJC18
DnaJ homolog subfamily C member 18

1

14

High-throughput

0.407

High

1230845

DJB12
DnaJ homolog subfamily B member 12

1

14

High-throughput

0.407

High

1230846

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

1

High-throughput

0.407

High

1230849

DJB11
DnaJ homolog subfamily B member 11

1

6

High-throughput

0.407

High

1230851

SE1L1
Protein sel-1 homolog 1

1

3

High-throughput

0.407

High

1230852

AMFR
E3 ubiquitin-protein ligase AMFR

1

5

High-throughput

0.407

High

1230853

BAG5
BAG family molecular chaperone regulator 5

1

8

High-throughput

0.407

High

1230854

CHIP
E3 ubiquitin-protein ligase CHIP

1

4

High-throughput

0.407

High

1230847

IL37
Interleukin-37

1

0

High-throughput

0.269

Low

1230848

RN181
E3 ubiquitin-protein ligase RNF181

1

0

High-throughput

0.269

Low

1198237

FND3B
Fibronectin type III domain-containing protein 3B

1

0

High-throughput

0.232

Low

1200504

TAF1B
TATA box-binding protein-associated factor RNA polymerase I subunit B

1

0

High-throughput

0.232

Low

1230836

F241B
Protein FAM241B

1

0

High-throughput

0.232

Low

1230850

FA8A1
Protein FAM8A1

1

0

High-throughput

0.232

Low

1230855

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025