Protein: ADCY3
Adenylate cyclase type 3 (EC 4.6.1.1) (ATP pyrophosphate-lyase 3) (Adenylate cyclase type III) (AC-III) (Adenylate cyclase, olfactive type) (Adenylyl cyclase 3) (AC3)

Gene: ADCY3
Organism: Homo sapiens
Interactions: 72
UniProt ID: O60266

Gene Ontology (top 5):
GO:0004016 - adenylate cyclase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

243807

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

2

5

High-throughput

0.811

High

243788

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.770

High

243784

LEG3
Galectin-3

4

10

High-throughput

0.691

High

142121

NPT3
Sodium-dependent phosphate transport protein 3

2

1

High-throughput

0.628

High

243800

CNGA3
Cyclic nucleotide-gated channel alpha-3

2

2

High-throughput

0.628

High

243801

S4A8
Electroneutral sodium bicarbonate exchanger 1

2

3

High-throughput

0.628

High

243841

PCDG5
Protocadherin gamma-A5

2

1

High-throughput

0.628

High

243789

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.618

High

243809

IZUM1
Izumo sperm-egg fusion protein 1

2

0

High-throughput

0.602

High

243812

I17RC
Interleukin-17 receptor C

2

0

High-throughput

0.602

High

243820

ASIC4
Acid-sensing ion channel 4

2

0

High-throughput

0.602

High

243824

ZNT2
Proton-coupled zinc antiporter SLC30A2

2

3

High-throughput

0.601

High

243794

RHOB
Rho-related GTP-binding protein RhoB

2

12

High-throughput

0.584

High

243783

CP19A
Aromatase

1

1

High-throughput

0.536

High

243785

KCNA5
Potassium voltage-gated channel subfamily A member 5

1

1

High-throughput

0.536

High

243786

NKG2C
NKG2-C type II integral membrane protein

1

1

High-throughput

0.536

High

243787

ACHB4
Neuronal acetylcholine receptor subunit beta-4

1

3

High-throughput

0.536

High

243802

TTMP
TPA-induced transmembrane protein

1

2

High-throughput

0.536

High

243811

M4A15
Membrane-spanning 4-domains subfamily A member 15

1

1

High-throughput

0.536

High

243821

TSN17
Tetraspanin-17

1

2

High-throughput

0.536

High

243822

ZDH12
Palmitoyltransferase ZDHHC12

1

2

High-throughput

0.536

High

243825

CA043
Protein C1orf43

1

2

High-throughput

0.536

High

243827

TTYH1
Protein tweety homolog 1

1

2

High-throughput

0.536

High

243829

RXFP1
Relaxin receptor 1

1

1

High-throughput

0.536

High

243830

KCMB3
Calcium-activated potassium channel subunit beta-3

1

1

High-throughput

0.536

High

243832

CP26B
Cytochrome P450 26B1

1

1

High-throughput

0.536

High

243835

CHIP
E3 ubiquitin-protein ligase CHIP

1

4

High-throughput

0.536

High

243839

O10H1
Olfactory receptor 10H1

1

1

High-throughput

0.536

High

243840

PCDB3
Protocadherin beta-3

1

1

High-throughput

0.536

High

243842

PTC2
Protein patched homolog 2

1

1

High-throughput

0.536

High

243843

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

1

High-throughput

0.536

High

243780

ADRB2
Beta-2 adrenergic receptor

1

0

Small-scale

0.529

High

213669

AQP9
Aquaporin-9

1

0

High-throughput

0.513

High

243777

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.513

High

243797

VPP3
V-type proton ATPase 116 kDa subunit a 3

1

0

High-throughput

0.513

High

243803

DCST1
E3 ubiquitin-protein ligase DCST1

1

0

High-throughput

0.513

High

243806

LHPL1
LHFPL tetraspan subfamily member 1 protein

1

0

High-throughput

0.513

High

243813

TLC3A
TLC domain-containing protein 3A

1

0

High-throughput

0.513

High

243816

CC107
Coiled-coil domain-containing protein 107

1

0

High-throughput

0.513

High

243818

TR19L
Tumor necrosis factor receptor superfamily member 19L

1

0

High-throughput

0.513

High

243826

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.513

High

243833

TLR9
Toll-like receptor 9

1

0

High-throughput

0.513

High

243792

MTR1B
Melatonin receptor type 1B

1

1

High-throughput

0.508

High

243798

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

1

High-throughput

0.489

High

243778

RASK
GTPase KRas

1

8

High-throughput

0.479

High

243781

LYN
Tyrosine-protein kinase Lyn

1

2

High-throughput

0.479

High

243795

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

243799

RAB35
Ras-related protein Rab-35

1

2

High-throughput

0.479

High

243828

POPD2
Popeye domain-containing protein 2

1

1

High-throughput

0.479

High

137350

NPT4
Sodium-dependent phosphate transport protein 4

1

1

High-throughput

0.445

High

170570

CLGN
Calmegin

1

3

High-throughput

0.445

High

243779

B3AT
Band 3 anion transport protein

1

3

High-throughput

0.445

High

243791

SL9A3
Sodium/hydrogen exchanger 3

1

3

High-throughput

0.445

High

243793

G6PT2
Glucose-6-phosphate exchanger SLC37A1

1

3

High-throughput

0.445

High

243796

NIPA4
Magnesium transporter NIPA4

1

2

High-throughput

0.445

High

243804

SL9A4
Sodium/hydrogen exchanger 4

1

3

High-throughput

0.445

High

243805

NPAL3
NIPA-like protein 3

1

2

High-throughput

0.445

High

243808

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

3

High-throughput

0.445

High

243814

GTR14
Solute carrier family 2, facilitated glucose transporter member 14

1

1

High-throughput

0.445

High

243819

FUCT1
GDP-fucose transporter 1

1

1

High-throughput

0.445

High

243823

B3A4
Anion exchange protein 4

1

3

High-throughput

0.445

High

243836

S12A4
Solute carrier family 12 member 4

1

5

High-throughput

0.445

High

243837

S27A6
Long-chain fatty acid transport protein 6

1

3

High-throughput

0.445

High

243838

S27A5
Long-chain fatty acid transport protein 5

1

3

High-throughput

0.445

High

243782

S35E2
Solute carrier family 35 member E2A

1

0

High-throughput

0.426

High

243790

EAA4
Excitatory amino acid transporter 4

1

0

High-throughput

0.426

High

243810

S22AO
Steroid transmembrane transporter SLC22A24

1

0

High-throughput

0.426

High

243817

CTL1
Choline transporter-like protein 1

1

0

High-throughput

0.426

High

243815

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

3

High-throughput

0.407

High

49764

CLRN2
Clarin-2

1

0

High-throughput

0.279

Low

243831

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.279

Low

243834

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025