HitPredict

Interactor 1: FOXA1 (P55317)
Hepatocyte nuclear factor 3-alpha (HNF-3-alpha) (HNF-3A) (Forkhead box protein A1) (Transcription factor 3A) (TCF-3A)
Gene: FOXA1

Interactor 2: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27926873
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 472 Hs			1 772
+	Hs
		877703 FOXA1_HUMAN (1-472): 5.65e-93: 291: 100.00		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Hs
		980742 FOXL1_HUMAN (143-337): 1.76e-55: 190: 42.86		TLE3_HUMAN (1-772): 0: 583: 100.00
+	Hs
		980669 FOXA2_HUMAN (1-472): 1.2e-66: 222: 42.62		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Hs
		980740 FOXC1_HUMAN (130-457): 7.84e-49: 177: 31.42		TLE3_HUMAN (1-772): 0: 583: 100.00
+	Hs
		877602 FOXG1_HUMAN (17-470): 1.3e-61: 210: 22.32		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Rn
		88552 FOXG1_RAT (17-470): 4.59e-64: 216: 23.18		D3ZCM7_RAT (1-772): 3.17e-177: 528: 77.94
+	Mm
		1141982 FOXG1_MOUSE (17-470): 2.18e-62: 212: 23.56		TLE1_MOUSE (1-772): 1.82e-174: 522: 78.22
+	Hs
		980596 FOXL1_HUMAN (143-337): 1.76e-55: 190: 42.86		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Hs
		980931 FOXL1_HUMAN (143-337): 1.76e-55: 190: 42.86		TLE4_HUMAN (1-772): 9.37e-179: 533: 80.65
+	Hs
		877990 FOXA3_HUMAN (1-414): 4.01e-48: 170: 38.65		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Hs
		877991 FOXA3_HUMAN (1-414): 4.01e-48: 170: 38.65		TLE2_HUMAN (1-772): 4.46e-145: 445: 62.10
+	Hs
		993408 FOXL1_HUMAN (143-337): 1.76e-55: 190: 42.86		TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19
+	Ce
		137682 FKH02_CAEEL (112-324): 1.26e-51: 177: 27.06		UNC37_CAEEL (18-686): 7.48e-82: 275: 17.09
+	Ce
		137678 UN130_CAEEL (51-373): 9.43e-50: 174: 25.00		UNC37_CAEEL (18-686): 7.48e-82: 275: 17.09
+	Hs
		877671 FOXA1_HUMAN (1-472): 5.65e-93: 291: 100.00		WDR5_HUMAN (284-560): 2.42e-32: 130: 9.12
+	Hs
		877636 FOXG1_HUMAN (17-470): 1.3e-61: 210: 22.32		TLE6_HUMAN (466-772): 1.05e-46: 177: 33.12
+	Hs
		952865 FOXK1_HUMAN (107-373): 2.04e-54: 195: 27.24		TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07
+	Hs
		1021159 FOXC1_HUMAN (130-457): 7.84e-49: 177: 31.42		TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07
+	Dm
		970548 FD3_DROME (92-273): 2.21e-53: 187: 42.86		Q9VVI0_DROME (550-763): 3.42e-14: 78.2: 27.35
+	Hs
		1021146 FOXC1_HUMAN (130-457): 7.84e-49: 177: 31.42		SNR40_HUMAN (509-677): 5.35e-09: 60.8: 26.52