HitPredict

Interactor 1: FOXA3 (P55318)
Hepatocyte nuclear factor 3-gamma (HNF-3-gamma) (HNF-3G) (Fork head-related protein FKH H3) (Forkhead box protein A3) (Transcription factor 3G) (TCF-3G)
Gene: FOXA3

Interactor 2: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25609649
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 350 Hs			1 772
+	Hs
		877990 FOXA3_HUMAN (1-350): 1.82e-94: 286: 100.00		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Hs
		877704 FOXA1_HUMAN (1-350): 3.39e-65: 215: 35.38		TLE3_HUMAN (1-772): 0: 583: 100.00
+	Hs
		980740 FOXC1_HUMAN (40-297): 2.17e-55: 191: 35.66		TLE3_HUMAN (1-772): 0: 583: 100.00
+	Hs
		980894 FOXJ2_HUMAN (58-307): 6.38e-53: 185: 31.20		TLE3_HUMAN (1-772): 0: 583: 100.00
+	Hs
		980669 FOXA2_HUMAN (1-350): 1.33e-70: 229: 35.45		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Hs
		980741 FOXI1_HUMAN (9-329): 1.45e-53: 182: 26.51		TLE3_HUMAN (1-772): 0: 583: 100.00
+	Hs
		877703 FOXA1_HUMAN (1-350): 3.39e-65: 215: 35.38		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Hs
		877991 FOXA3_HUMAN (1-350): 1.82e-94: 286: 100.00		TLE2_HUMAN (1-772): 4.46e-145: 445: 62.10
+	Hs
		877602 FOXG1_HUMAN (115-321): 2.09e-54: 187: 37.80		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Hs
		980595 FOXI1_HUMAN (9-329): 1.45e-53: 182: 26.51		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Rn
		88552 FOXG1_RAT (38-321): 3.07e-55: 189: 32.87		D3ZCM7_RAT (1-772): 3.17e-177: 528: 77.94
+	Mm
		1141982 FOXG1_MOUSE (38-321): 3.9e-55: 189: 32.87		TLE1_MOUSE (1-772): 1.82e-174: 522: 78.22
+	Hs
		1021159 FOXC1_HUMAN (40-297): 2.17e-55: 191: 35.66		TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07
+	Hs
		952865 FOXK1_HUMAN (16-319): 4.74e-54: 191: 25.96		TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07
+	Hs
		877636 FOXG1_HUMAN (115-321): 2.09e-54: 187: 37.80		TLE6_HUMAN (466-772): 1.05e-46: 177: 33.12
+	Hs
		964245 FOXK2_HUMAN (20-312): 6.64e-54: 189: 28.62		TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07
+	Hs
		877671 FOXA1_HUMAN (1-350): 3.39e-65: 215: 35.38		WDR5_HUMAN (284-560): 2.42e-32: 130: 9.12
+	Hs
		154676 FOXK2_HUMAN (20-312): 6.64e-54: 189: 28.62		GNB5_HUMAN (609-770): 9.68e-25: 109: 18.50
+	Dm
		970548 FD3_DROME (36-256): 3.23e-62: 207: 33.48		Q9VVI0_DROME (550-763): 3.42e-14: 78.2: 27.35
+	Hs
		1021146 FOXC1_HUMAN (40-297): 2.17e-55: 191: 35.66		SNR40_HUMAN (509-677): 5.35e-09: 60.8: 26.52