HitPredict

Interactor 1: RIPK4 (P57078)
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)
Gene: RIPK4

Interactor 2: FKBP3 (Q00688)
Peptidyl-prolyl cis-trans isomerase FKBP3 (PPIase FKBP3) (EC 5.2.1.8) (25 kDa FK506-binding protein) (25 kDa FKBP) (FKBP-25) (FK506-binding protein 3) (FKBP-3) (Immunophilin FKBP25) (Rapamycin-selective 25 kDa immunophilin) (Rotamase)
Gene: FKBP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	32707033
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	FKBP_C~Pkinase
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 832 Hs			1 224
+	Hs
		961567 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKBP3_HUMAN (1-224): 1.38e-101: 295: 100.00
+	Hs
		883470 RIPK4_HUMAN (1-832): 0: 726: 100.00		FKB1A_HUMAN (109-224): 4.55e-49: 157: 38.79
+	Hs
		923838 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKB1A_HUMAN (109-224): 4.55e-49: 157: 38.79
+	Hs
		883489 RIPK4_HUMAN (1-832): 0: 726: 100.00		FKBP4_HUMAN (74-224): 6.73e-17: 80.5: 24.68
+	Hs
		883504 RIPK4_HUMAN (1-832): 0: 726: 100.00		FKBP5_HUMAN (76-224): 5.61e-14: 72.1: 23.03
+	Hs
		972586 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKBP4_HUMAN (74-224): 6.73e-17: 80.5: 24.68
+	Hs
		1034995 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKBP5_HUMAN (76-224): 5.61e-14: 72.1: 23.03
+	Hs
		1034933 ANKK1_HUMAN (342-643): 1.15e-46: 180: 19.47		FKBP5_HUMAN (76-224): 5.61e-14: 72.1: 23.03
+	Hs
		972616 RIPK3_HUMAN (21-371): 4.07e-34: 139: 30.39		FKBP4_HUMAN (74-224): 6.73e-17: 80.5: 24.68
+	Hs
		1035071 RIPK3_HUMAN (21-371): 4.07e-34: 139: 30.39		FKBP5_HUMAN (76-224): 5.61e-14: 72.1: 23.03