HitPredict

Interactor 1: JAM2 (P57087)
Junctional adhesion molecule B (JAM-B) (Junctional adhesion molecule 2) (JAM-2) (Vascular endothelial junction-associated molecule) (VE-JAM) (CD antigen CD322)
Gene: JAM2

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	12953056, 17057644
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction GO:0070160 - tight junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 298 Hs			1 1356
+	Hs
		1256876 JAM3_HUMAN (1-298): 5.16e-57: 187: 34.08		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		1256929 JAM1_HUMAN (1-298): 6.57e-56: 184: 34.11		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		508120 FGFR1_HUMAN (40-283): 4.41e-43: 159: 19.46		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		940506 CXAR_HUMAN (10-286): 7.65e-45: 157: 20.74		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Rn
		1337448 JAM1_RAT (4-298): 5.11e-53: 176: 34.22		PARD3_RAT (1-1356): 0: 685: 89.68
+	Hs
		940598 CXAR_HUMAN (10-286): 7.65e-45: 157: 20.74		NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36
+	Mm
		292319 JAM1_MOUSE (4-298): 7.36e-53: 176: 34.22		MPDZ_MOUSE (452-543): 1.11e-20: 101: 42.39
+	Hs
		883795 JAM2_HUMAN (18-298): 2.87e-61: 198: 100.00		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Mm
		956922 CXAR_MOUSE (11-280): 8.22e-47: 162: 22.53		LNX2_MOUSE (15-361): 1.42e-19: 97: 11.11
+	Hs
		990924 JAM3_HUMAN (1-298): 5.16e-57: 187: 34.08		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Hs
		940491 CXAR_HUMAN (10-286): 7.65e-45: 157: 20.74		LNX2_HUMAN (50-361): 6.83e-21: 101: 11.35
+	Hs
		990962 JAM1_HUMAN (1-298): 6.57e-56: 184: 34.11		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Hs
		507970 FGFR1_HUMAN (40-283): 4.41e-43: 159: 19.46		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		940410 CXAR_HUMAN (10-286): 7.65e-45: 157: 20.74		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		940533 CXAR_HUMAN (10-286): 7.65e-45: 157: 20.74		MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16
+	Mm
		250614 CXAR_MOUSE (11-280): 8.22e-47: 162: 22.53		LNX1_MOUSE (130-385): 1.31e-14: 80.8: 15.33
+	Hs
		940504 CXAR_HUMAN (10-286): 7.65e-45: 157: 20.74		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		940406 CXAR_HUMAN (10-286): 7.65e-45: 157: 20.74		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Hs
		507995 FGFR1_HUMAN (40-283): 4.41e-43: 159: 19.46		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		940421 CXAR_HUMAN (10-286): 7.65e-45: 157: 20.74		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75