HitPredict

Interactor 1: FOXL2 (P58012)
Forkhead box protein L2
Gene: FOXL2

Interactor 2: TTF2 (Q9UNY4)
Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2)
Gene: TTF2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25609649
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 376 Hs			1 1162
+	Hs
		877716 FOXA1_HUMAN (10-340): 9.06e-47: 167: 26.55		CHD3_HUMAN (170-1160): 0: 613: 15.72
+	Dm
		631310 FOXO_DROME (6-266): 2.02e-45: 166: 23.79		BRM_DROME (125-1162): 0: 590: 16.07
+	Hs
		1021365 FOXL1_HUMAN (28-215): 7.39e-48: 167: 45.21		CHD7_HUMAN (93-1160): 9.11e-179: 585: 15.23
+	Hs
		877612 FOXG1_HUMAN (11-334): 5.9e-50: 176: 27.80		CHD4_HUMAN (172-1160): 3.82e-178: 573: 15.46
+	Dm
		332812 FOXO_DROME (6-266): 2.02e-45: 166: 23.79		CHDM_DROME (53-1160): 2.73e-179: 578: 16.06
+	Hs
		877733 FOXA1_HUMAN (10-340): 9.06e-47: 167: 26.55		CHD4_HUMAN (172-1160): 3.82e-178: 573: 15.46
+	Hs
		229476 FOXC2_HUMAN (4-360): 3.03e-54: 188: 29.13		SMCA5_HUMAN (452-1162): 1.14e-175: 546: 20.03
+	Hs
		229346 FOXG1_HUMAN (11-334): 5.9e-50: 176: 27.80		SMCA5_HUMAN (452-1162): 1.14e-175: 546: 20.03
+	Hs
		877638 FOXG1_HUMAN (11-334): 5.9e-50: 176: 27.80		HELLS_HUMAN (378-1160): 8.61e-176: 540: 18.30
+	Hs
		229381 FOXL1_HUMAN (28-215): 7.39e-48: 167: 45.21		SMCA5_HUMAN (452-1162): 1.14e-175: 546: 20.03
+	Dm
		1097629 FOXO_DROME (6-266): 2.02e-45: 166: 23.79		ISWI_DROME (450-1158): 2.07e-174: 542: 19.40
+	Hs
		1021359 FOXL1_HUMAN (28-215): 7.39e-48: 167: 45.21		HELLS_HUMAN (378-1160): 8.61e-176: 540: 18.30
+	Hs
		658644 FOXG1_HUMAN (11-334): 5.9e-50: 176: 27.80		SMCA1_HUMAN (453-1159): 1.32e-167: 525: 21.75
+	Hs
		658662 FOXL1_HUMAN (28-215): 7.39e-48: 167: 45.21		SMCA1_HUMAN (453-1159): 1.32e-167: 525: 21.75
+	Dm
		713054 FOXO_DROME (6-266): 2.02e-45: 166: 23.79		TTF2_DROME (211-1162): 1.43e-166: 523: 31.38
+	Hs
		163591 FOXL2_HUMAN (1-376): 1.34e-71: 230: 100.00		BTAF1_HUMAN (563-1160): 1.99e-41: 168: 27.38
+	Hs
		163590 FOXG1_HUMAN (11-334): 5.9e-50: 176: 27.80		BTAF1_HUMAN (563-1160): 1.99e-41: 168: 27.38
+	Hs
		163600 FOXL1_HUMAN (28-215): 7.39e-48: 167: 45.21		BTAF1_HUMAN (563-1160): 1.99e-41: 168: 27.38
+	Sp
		145302 FHL1_SCHPO (27-360): 3.96e-44: 164: 22.95		FFT3_SCHPO (548-1148): 4.54e-34: 144: 26.70
+	Dm
		1279980 FOXO_DROME (6-266): 2.02e-45: 166: 23.79		Q9VPL9_DROME (65-561): 2.58e-13: 77.4: 8.98