HitPredict

Interactor 1: EPIPL (P58107)
Epiplakin (450 kDa epidermal antigen)
Gene: EPPK1

Interactor 2: KT33B (Q14525)
Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3-II) (Keratin-33B) (K33B)
Gene: KRT33B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005198 - structural molecule activity GO:0005856 - cytoskeleton GO:0045109 - intermediate filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 5088 Hs			1 404
+	Hs
		359323 EPIPL_HUMAN (1-5088): 0: 4242: 100.00		K1C14_HUMAN (54-367): 2.81e-143: 417: 60.51
+	Hs
		885269 EPIPL_HUMAN (1-5088): 0: 4242: 100.00		K2C73_HUMAN (3-404): 3.49e-99: 307: 23.02
+	Hs
		213934 EPIPL_HUMAN (1-5088): 0: 4242: 100.00		KRT86_HUMAN (5-402): 5.14e-94: 292: 24.81
+	Hs
		318791 EPIPL_HUMAN (1-5088): 0: 4242: 100.00		K2C75_HUMAN (21-381): 6.17e-90: 283: 25.34
+	Hs
		885251 EPIPL_HUMAN (1-5088): 0: 4242: 100.00		K2C72_HUMAN (3-404): 5.19e-87: 275: 23.02
+	Hs
		885321 EPIPL_HUMAN (1-5088): 0: 4242: 100.00		KRT82_HUMAN (5-394): 6.22e-87: 274: 24.04
+	Hs
		885248 EPIPL_HUMAN (1-5088): 0: 4242: 100.00		K1H2_HUMAN (5-402): 4.61e-84: 265: 66.67
+	Hs
		885254 EPIPL_HUMAN (1-5088): 0: 4242: 100.00		K1H1_HUMAN (1-392): 8.95e-80: 253: 94.64
+	Mm
		513795 DMD_MOUSE (1908-3539): 4.34e-135: 482: 10.64		K1C40_MOUSE (5-402): 1.34e-149: 432: 61.31
+	Rn
		513772 DMD_RAT (1908-3539): 9.79e-136: 484: 10.58		K1C19_RAT (47-369): 1.52e-146: 423: 55.73
+	Hs
		359355 PLEC_HUMAN (1149-4489): 2.53e-72: 275: 17.38		K1C14_HUMAN (54-367): 2.81e-143: 417: 60.51
+	Hs
		444372 PLEC_HUMAN (1149-4489): 2.53e-72: 275: 17.38		K1C19_HUMAN (49-366): 1.39e-142: 413: 55.98
+	Hs
		1068566 PLEC_HUMAN (1149-4489): 2.53e-72: 275: 17.38		K1C39_HUMAN (40-399): 1.66e-128: 380: 61.56
+	Hs
		445052 PLEC_HUMAN (1149-4489): 2.53e-72: 275: 17.38		K1C16_HUMAN (54-369): 2.62e-110: 333: 59.81
+	Hs
		280584 PLEC_HUMAN (1149-4489): 2.53e-72: 275: 17.38		KRT34_HUMAN (1-388): 2.98e-92: 284: 89.95
+	Hs
		444307 DESP_HUMAN (2873-5087): 3.05e-30: 135: 10.82		K1C19_HUMAN (49-366): 1.39e-142: 413: 55.98
+	Hs
		821662 PLEC_HUMAN (1149-4489): 2.53e-72: 275: 17.38		K2C6C_HUMAN (21-391): 1.57e-79: 256: 24.13
+	Hs
		551676 DESP_HUMAN (2873-5087): 3.05e-30: 135: 10.82		K1C17_HUMAN (49-367): 1.46e-113: 340: 59.88
+	Hs
		531529 DESP_HUMAN (2873-5087): 3.05e-30: 135: 10.82		K2C5_HUMAN (21-377): 6.67e-79: 256: 25.07
+	Hs
		359462 DESP_HUMAN (2873-5087): 3.05e-30: 135: 10.82		K2C6A_HUMAN (21-391): 5.01e-78: 253: 24.13