Protein: NR1D2
Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear hormone receptor BD73) (Rev-erb alpha-related receptor) (RVR) (Rev-erb-beta) (V-erbA-related protein 1-related) (EAR-1R)

Gene: NR1D2
Organism: Homo sapiens
Interactions: 75
UniProt ID: Q14995

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

631836

NR1D1
Nuclear receptor subfamily 1 group D member 1

2

16

High-throughput

0.789

High

902780

RORG
Nuclear receptor ROR-gamma

1

17

High-throughput

0.656

High

1134828

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

3

10

Small-scale

0.656

High

1134826

NT2NA
Notch homolog 2 N-terminal-like protein A

3

6

High-throughput

0.635

High

1134851

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

20

High-throughput

0.621

High

1134848

ZN703
Zinc finger protein 703

2

12

High-throughput

0.611

High

1134853

SATB2
DNA-binding protein SATB2

2

2

High-throughput

0.611

High

1109733

HDAC1
Histone deacetylase 1

2

20

Small-scale

0.602

High

932073

EPHA4
Ephrin type-A receptor 4

1

10

High-throughput

0.590

High

571980

TRI27
Zinc finger protein RFP

2

7

High-throughput

0.584

High

1134839

ANM6
Protein arginine N-methyltransferase 6

1

18

High-throughput

0.573

High

1134835

KAT5
Histone acetyltransferase KAT5

1

7

Small-scale

0.561

High

192923

CLOCK
Circadian locomoter output cycles protein kaput

1

20

High-throughput

0.552

High

923597

TTC3
E3 ubiquitin-protein ligase TTC3

1

13

High-throughput

0.541

High

1134844

KRA42
Keratin-associated protein 4-2

2

20

High-throughput

0.533

High

116859

I6L9F6
NEFL protein

1

20

High-throughput

0.515

High

186910

GPR37
Prosaposin receptor GPR37

1

1

High-throughput

0.515

High

245942

KIF1B
Kinesin-like protein KIF1B

1

7

High-throughput

0.515

High

301428

WFS1
Wolframin

1

1

High-throughput

0.515

High

415575

HSPB1
Heat shock protein beta-1

1

6

High-throughput

0.515

High

442320

GELS
Gelsolin

1

7

High-throughput

0.515

High

1134827

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

7

High-throughput

0.515

High

1134852

UBQL1
Ubiquilin-1

1

11

High-throughput

0.515

High

1134854

RNF11
RING finger protein 11

1

5

High-throughput

0.515

High

625388

CSK22
Casein kinase II subunit alpha'

1

11

High-throughput

0.508

High

274329

SIN3B
Paired amphipathic helix protein Sin3b

1

5

Small-scale

0.501

High

278349

NCOR1
Nuclear receptor corepressor 1

1

20

Small-scale

0.501

High

892021

TAF6
Transcription initiation factor TFIID subunit 6

1

4

Small-scale

0.501

High

1025101

TF2B
Transcription initiation factor IIB

1

3

Small-scale

0.501

High

1134822

TAF9
Transcription initiation factor TFIID subunit 9

1

4

Small-scale

0.501

High

705341

GRN
Progranulin

1

0

High-throughput

0.493

High

519

NBPFJ
NBPF family member NBPF19

1

6

High-throughput

0.481

High

127332

LEG8
Galectin-8

1

7

High-throughput

0.481

High

277096

PROP1
Homeobox protein prophet of Pit-1

1

20

High-throughput

0.481

High

885247

HXA1
Homeobox protein Hox-A1

1

19

High-throughput

0.481

High

885778

KC1E
Casein kinase I isoform epsilon

1

13

High-throughput

0.481

High

893868

MEOX2
Homeobox protein MOX-2

1

20

High-throughput

0.481

High

1134820

TRIP6
Thyroid receptor-interacting protein 6

1

16

High-throughput

0.481

High

1134821

CRY1
Cryptochrome-1

1

2

High-throughput

0.481

High

1134833

MYLIP
E3 ubiquitin-protein ligase MYLIP

1

10

High-throughput

0.481

High

1134836

RBPMS
RNA-binding protein with multiple splicing

1

1

High-throughput

0.481

High

1134837

TRI63
E3 ubiquitin-protein ligase TRIM63

1

20

High-throughput

0.481

High

1134838

TET5B
Terminal nucleotidyltransferase 5B

1

3

High-throughput

0.481

High

1134840

ZN587
Zinc finger protein 587

1

8

High-throughput

0.481

High

1134847

TRI55
Tripartite motif-containing protein 55

1

20

High-throughput

0.481

High

1095251

REST
RE1-silencing transcription factor

1

3

High-throughput

0.479

High

1113130

CUL3
Cullin-3

1

13

High-throughput

0.479

High

1134832

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

47331

A0A6Q8PF08
Peripheral myelin protein 22

1

1

High-throughput

0.470

High

109405

G5E9A7
DM1 locus, WD repeat containing

1

20

High-throughput

0.470

High

650166

FGFR3
Fibroblast growth factor receptor 3

1

7

High-throughput

0.470

High

1134829

Q86WV8
TSC complex subunit 1

1

3

High-throughput

0.470

High

154981

BHE40
Class E basic helix-loop-helix protein 40

1

19

High-throughput

0.457

High

70211

CRTP1
Cysteine-rich tail protein 1

1

1

High-throughput

0.439

High

351538

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

6

High-throughput

0.439

High

948320

KR122
Keratin-associated protein 12-2

1

20

High-throughput

0.439

High

949538

KR123
Keratin-associated protein 12-3

1

3

High-throughput

0.439

High

949695

KR101
Keratin-associated protein 10-1

1

20

High-throughput

0.439

High

950481

KR108
Keratin-associated protein 10-8

1

20

High-throughput

0.439

High

950761

KR109
Keratin-associated protein 10-9

1

20

High-throughput

0.439

High

1059634

KRA11
Keratin-associated protein 1-1

1

20

High-throughput

0.439

High

1134823

KRA62
Keratin-associated protein 6-2

1

1

High-throughput

0.439

High

1134824

K1C40
Keratin, type I cytoskeletal 40

1

17

High-throughput

0.439

High

1134825

KRA56
Keratin-associated protein 5-6

1

1

High-throughput

0.439

High

1134830

KRA13
Keratin-associated protein 1-3

1

20

High-throughput

0.439

High

1134831

TBC21
TBC1 domain family member 21

1

4

High-throughput

0.439

High

1134834

PCSK5
Proprotein convertase subtilisin/kexin type 5

1

4

High-throughput

0.439

High

1134841

KRA98
Keratin-associated protein 9-8

1

20

High-throughput

0.439

High

1134842

KRA93
Keratin-associated protein 9-3

1

20

High-throughput

0.439

High

1134843

KRA92
Keratin-associated protein 9-2

1

20

High-throughput

0.439

High

1134845

KRA33
Keratin-associated protein 3-3

1

3

High-throughput

0.439

High

1134846

KRA32
Keratin-associated protein 3-2

1

3

High-throughput

0.439

High

1134850

DEC1
Deleted in esophageal cancer 1

1

2

High-throughput

0.439

High

1134849

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.417

High

1134855

Q9Y649
GW128

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025