HitPredict

Interactor 1: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Interactor 2: NHP10 (Q03435)
Non-histone protein 10 (High mobility group protein 2)
Gene: NHP10

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	11805826, 37968396, 16429126, 15607974
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006281 - DNA repair GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription GO:0031011 - Ino80 complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 375 Sc			1 203
+	Hs
		818119 ACTBL_HUMAN (2-375): 0: 687: 83.42		SOX2_HUMAN (63-178): 1.49e-29: 112: 15.00
+	Hs
		932341 ACTC_HUMAN (2-375): 0: 591: 87.17		CIC_HUMAN (44-201): 6.64e-29: 114: 16.76
+	Hs
		175761 ACTB_HUMAN (1-375): 0: 601: 88.80		HMGB3_HUMAN (90-160): 1.02e-23: 94.9: 32.00
+	Sc
		514201 ACT_YEAST (1-375): 0: 594: 100.00		NHP6A_YEAST (78-162): 3.8e-25: 95.6: 31.46
+	Hs
		449663 ACTC_HUMAN (2-375): 0: 591: 87.17		HMGB1_HUMAN (80-160): 1.31e-19: 84.5: 31.77