HitPredict

Interactor 1: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Interactor 2: RUVB1 (Q03940)
RuvB-like protein 1 (RUVBL1) (EC 3.6.4.12) (TIP49-homology protein 1) (TIP49a homolog)
Gene: RVB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.943

The method score is based on:

Property Details
Experiments 30177756, 11278922, 16429126, 26831523, 31914392, 37968396
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~TIP49
Common GO terms GO:0000785 - chromatin
GO:0000812 - Swr1 complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006281 - DNA repair
and 4 others

more...
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 375
Sc

1 463
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024