HitPredict

Interactor 1: PSB2 (P49721)
Proteasome subunit beta type-2 (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I) (Proteasome subunit beta-4) (beta-4)
Gene: PSMB2

Interactor 2: PSMF1 (Q92530)
Proteasome inhibitor PI31 subunit (hPI31)
Gene: PSMF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PI31_Prot_C~Proteasome
Common GO terms	GO:0005829 - cytosol GO:0005839 - proteasome core complex GO:0016020 - membrane GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 201 Hs			1 271
+	Hs
		1363752 PSB7_HUMAN (3-199): 1.33e-64: 202: 19.80		PSMF1_HUMAN (1-271): 3.21e-157: 439: 100.00
+	Hs
		681692 PSA4_HUMAN (3-198): 5.78e-65: 202: 17.73		PSMF1_HUMAN (1-271): 3.21e-157: 439: 100.00
+	Hs
		681206 PSA2_HUMAN (4-197): 1.05e-64: 201: 17.86		PSMF1_HUMAN (1-271): 3.21e-157: 439: 100.00
+	Hs
		633756 PSB1_HUMAN (3-198): 2.08e-57: 182: 23.42		PSMF1_HUMAN (1-271): 3.21e-157: 439: 100.00