Interactor 1: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2
Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.90 | 1.00 | 0.949 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25963833, 19862764, 28514442, 27248496, 33961781, 26167883 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification, anti bait coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CENP-T_C~MCM2_N |
| Common GO terms | GO:0000781 - chromosome, telomeric region GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
