HitPredict

Interactor 1: RUVB1 (P60122)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (DNA helicase p50) (Pontin 52) (TIP49a)
Gene: Ruvbl1

Interactor 2: Q60I23 (Q60I23)
SRY (sex determining region Y)-box 2 (Sox2 protein) (Transcriptional factor SOX2)
Gene: Sox2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	21532573
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 456 Mm			1 319
+	Mm
		818680 RUVB1_MOUSE (1-456): 0: 716: 100.00		SOX2_MOUSE (1-319): 1.13e-62: 203: 98.43
+	Hs
		818624 RUVB1_HUMAN (1-456): 0: 715: 99.78		SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24
+	Hs
		1301007 RUVB1_HUMAN (1-456): 0: 715: 99.78		CIC_HUMAN (10-274): 1.46e-36: 141: 24.28
+	Mm
		1142023 RUVB2_MOUSE (2-455): 0: 649: 42.76		Q60I23_MOUSE (1-319): 7.44e-64: 206: 100.00
+	Mm
		818777 RUVB2_MOUSE (2-455): 0: 649: 42.76		SOX2_MOUSE (1-319): 1.13e-62: 203: 98.43
+	Hs
		818621 RUVB2_HUMAN (2-455): 0: 649: 42.76		SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24
+	Hs
		1301006 RUVB2_HUMAN (2-455): 0: 649: 42.76		CIC_HUMAN (10-274): 1.46e-36: 141: 24.28