Protein: MCM4
DNA replication licensing factor MCM4 (EC 3.6.4.12) (Protein disc proliferation abnormal)

Gene: MCM4, dpa
Organism: Drosophila melanogaster
Interactions: 77
UniProt ID: Q26454

Gene Ontology (top 5):
GO:0000727 - double-strand break repair via break-induced replication
GO:0003678 - DNA helicase activity
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1176016

MCM5
DNA replication licensing factor Mcm5

5

19

Small-scale

0.898

High

1176006

MCM6
DNA replication licensing factor Mcm6

4

20

Small-scale

0.896

High

356170

O96989
CDC45L

4

15

Small-scale

0.878

High

1176042

MCM7
DNA replication licensing factor Mcm7

3

20

Small-scale

0.827

High

887787

MCM2
DNA replication licensing factor Mcm2

2

19

Small-scale

0.754

High

1176043

MCM3
DNA replication licensing factor Mcm3

2

20

Small-scale

0.737

High

1176025

PSF2
Probable DNA replication complex GINS protein PSF2

1

11

Small-scale

0.691

High

1176010

Q9VBI1
DNA replication complex GINS protein SLD5

1

14

Small-scale

0.618

High

1176039

Q9W2V7
DNA replication complex GINS protein PSF3

1

9

Small-scale

0.618

High

262661

LOK
Ovarian-specific serine/threonine-protein kinase Lok

1

9

Small-scale

0.501

High

1176040

CDC7
non-specific serine/threonine protein kinase Cdc7

1

16

Small-scale

0.501

High

263518

MK38B
Mitogen-activated protein kinase p38b

1

10

Small-scale

0.479

High

1013257

MK14C
Putative mitogen-activated protein kinase 14C

1

10

Small-scale

0.479

High

1176023

KDM5
Lysine-specific demethylase 5

1

13

High-throughput

0.479

High

1176038

Q9W1G7
LD21576p

1

5

High-throughput

0.479

High

58081

A1ZBE9
Methionine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.445

High

437986

PYR1
Multifunctional protein r

1

6

High-throughput

0.445

High

704350

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

4

High-throughput

0.445

High

782710

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

1

3

High-throughput

0.445

High

852931

ACTZ
Actin-related protein 1

1

5

High-throughput

0.445

High

875204

TCPG
T-complex protein 1 subunit gamma

1

5

High-throughput

0.445

High

909860

PFKA
ATP-dependent 6-phosphofructokinase

1

5

High-throughput

0.445

High

1173896

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

6

High-throughput

0.445

High

1175996

Q8SY39
ATP-dependent RNA helicase DDX54

1

10

High-throughput

0.445

High

1175998

Q8T4G5
AFG3 like matrix AAA peptidase subunit 2, isoform A

1

1

High-throughput

0.445

High

1175999

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

3

High-throughput

0.445

High

1176001

Q9V3V6
26S proteasome regulatory complex subunit p50

1

3

High-throughput

0.445

High

1176002

Q9V405
26S proteasome regulatory subunit 6B

1

1

High-throughput

0.445

High

1176004

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.445

High

1176005

Q9V455
Importin subunit alpha

1

6

High-throughput

0.445

High

1176008

Q9VAH7
N-terminal kinase-like protein

1

2

High-throughput

0.445

High

1176011

DDX18
Probable ATP-dependent RNA helicase pitchoune

1

10

High-throughput

0.445

High

1176017

Q9VH81
protein-serine/threonine phosphatase

1

1

High-throughput

0.445

High

1176019

DDX47
ATP-dependent RNA helicase DDX47

1

9

High-throughput

0.445

High

1176021

NFS1
Cysteine desulfurase, mitochondrial

1

1

High-throughput

0.445

High

1176022

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

3

High-throughput

0.445

High

1176028

AIMP2
Probable aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

1

High-throughput

0.445

High

1176029

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

1

3

High-throughput

0.445

High

1176031

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.445

High

1176032

Q9VXR5
ATP-binding cassette sub-family F member 2

1

7

High-throughput

0.445

High

1176033

RENT1
Regulator of nonsense transcripts 1 homolog

1

4

High-throughput

0.445

High

1176034

Q9VZ88
AT07585p

1

11

High-throughput

0.445

High

1176041

Q9W414
Regulatory particle triple-A ATPase 4

1

1

High-throughput

0.445

High

1176045

SYQ
Probable glutamine--tRNA ligase

1

3

High-throughput

0.445

High

1175995

Q8MSW0
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

1176003

API5
Apoptosis inhibitor 5 homolog

1

0

High-throughput

0.426

High

53119

A1Z7K8
AaRS-interacting multifunctional protein 1

1

1

High-throughput

0.407

High

55428

A1Z9E3
Elongation factor Tu

1

5

High-throughput

0.407

High

55769

A1Z9K0
Uncharacterized protein, isoform B

1

4

High-throughput

0.407

High

118855

M9NFI9
Neurabin-1

1

1

High-throughput

0.407

High

262793

TENM
Teneurin-m

1

3

High-throughput

0.407

High

852180

COPB
Coatomer subunit beta

1

2

High-throughput

0.407

High

1069730

Q0E931
GTP-binding protein 1

1

9

High-throughput

0.407

High

1175991

SARM1
NAD(+) hydrolase sarm1

1

5

High-throughput

0.407

High

1175997

Q8SY53
GH11935p

1

3

High-throughput

0.407

High

1176000

Q95WY3
Nucleolar protein 56

1

1

High-throughput

0.407

High

1176007

Q9V9Q4
LD43819p

1

2

High-throughput

0.407

High

1176009

Q9VAW3
glutamine--fructose-6-phosphate transaminase

1

4

High-throughput

0.407

High

1176012

Q9VDK7
Signal recognition particle subunit SRP72

1

1

High-throughput

0.407

High

1176013

Q9VEH0
Aluminum tubes, isoform A

1

20

High-throughput

0.407

High

1176015

IPO9
Importin-9

1

7

High-throughput

0.407

High

1176018

Q9VI53
LD44267p

1

4

High-throughput

0.407

High

1176026

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.407

High

1176030

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

1

High-throughput

0.407

High

1176035

Q9VZU8
Alpha-1,3/1,6-mannosyltransferase ALG2

1

1

High-throughput

0.407

High

1176044

Q9XZ53
dolichyl-diphosphooligosaccharide--protein glycotransferase

1

1

High-throughput

0.407

High

263373

PENG
Protein penguin

1

0

High-throughput

0.232

Low

360536

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.232

Low

1175992

Q7JXU4
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.232

Low

1175993

Q7K3W4
GH08941p

1

0

High-throughput

0.232

Low

1175994

DYM
Dymeclin

1

0

High-throughput

0.232

Low

1176014

Q9VEP0
Regulatory protein zeste

1

0

High-throughput

0.232

Low

1176020

Q9VKA1
FI02817p

1

0

High-throughput

0.232

Low

1176024

Q9VQI5
Interferon-related developmental regulator 1

1

0

High-throughput

0.232

Low

1176027

FRL
Formin-like protein

1

0

High-throughput

0.232

Low

1176036

Q9W0E4
Aminopeptidase

1

0

High-throughput

0.232

Low

1176037

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025