Interactor 1: MCM2 (P49735)
DNA replication licensing factor Mcm2 (EC 3.6.4.12) (Minichromosome maintenance 2 protein) (DmMCM2)
Gene: MCM2
Interactor 2: MCM6 (Q9V461)
DNA replication licensing factor Mcm6 (DmMCM6) (EC 3.6.4.12)
Gene: MCM6
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.85 | 1.00 | 0.924 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25117490, 22036573, 16798881, 38944040, 11726693 |
| Identification Methods | pull down, affinity chromatography technology, anti tag coimmunoprecipitation, cross-linking study, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | MCM~MCM, MCM~MCM6_C, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM6_C~MCM_lid, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB |
| Common GO terms | GO:0000727 - double-strand break repair via break-induced replication GO:0003697 - single-stranded DNA binding GO:0005524 - ATP binding GO:0005634 - nucleus GO:0006260 - DNA replication and 6 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
