Protein: MCM2
DNA replication licensing factor Mcm2 (EC 3.6.4.12) (Minichromosome maintenance 2 protein) (DmMCM2)

Gene: MCM2
Organism: Drosophila melanogaster
Interactions: 56
UniProt ID: P49735

Gene Ontology (top 5):
GO:0000727 - double-strand break repair via break-induced replication
GO:0003697 - single-stranded DNA binding
GO:0004386 - helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

887797

MCM6
DNA replication licensing factor Mcm6

5

20

Small-scale

0.924

High

887805

MCM5
DNA replication licensing factor Mcm5

5

20

Small-scale

0.920

High

356169

O96989
CDC45L

4

16

Small-scale

0.890

High

887834

MCM3
DNA replication licensing factor Mcm3

3

20

Small-scale

0.839

High

887787

MCM4
DNA replication licensing factor MCM4

2

19

Small-scale

0.754

High

887814

PSF2
Probable DNA replication complex GINS protein PSF2

1

9

Small-scale

0.691

High

887798

ASF1
Histone chaperone asf1

1

11

High-throughput

0.618

High

887803

Q9VBI1
DNA replication complex GINS protein SLD5

1

14

Small-scale

0.618

High

887831

Q9W2V7
DNA replication complex GINS protein PSF3

1

8

Small-scale

0.618

High

887807

MCM10
Protein MCM10 homolog

2

14

Small-scale

0.606

High

887789

Q494K2
Chromosome transmission fidelity 4

2

17

Small-scale

0.526

High

887832

CDC7
non-specific serine/threonine protein kinase Cdc7

1

17

Small-scale

0.501

High

887829

Q9W1G7
LD21576p

1

4

High-throughput

0.479

High

887813

Q9VQG9
Dawdle, isoform A

1

2

High-throughput

0.464

High

56818

A1ZAK3
Protein DEK

1

1

High-throughput

0.445

High

847853

SNRPA
U1 small nuclear ribonucleoprotein A

1

5

High-throughput

0.445

High

887786

SET
Protein SET

1

5

High-throughput

0.445

High

887794

NASP
Nuclear autoantigenic sperm protein homolog

1

1

High-throughput

0.445

High

887796

Q9V3V9
Endonuclease G inhibitor, isoform A

1

1

High-throughput

0.445

High

887800

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

3

High-throughput

0.445

High

887808

RAGP1
Ran GTPase-activating protein

1

7

High-throughput

0.445

High

887815

DBR1
Lariat debranching enzyme

1

1

High-throughput

0.445

High

887818

Q9VUR4
FI11905p

1

8

High-throughput

0.445

High

887819

SMN
Survival motor neuron protein

1

1

High-throughput

0.445

High

887823

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.445

High

887825

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

2

High-throughput

0.445

High

887835

DDB1
DNA damage-binding protein 1

1

1

High-throughput

0.445

High

887836

SYQ
Probable glutamine--tRNA ligase

1

3

High-throughput

0.445

High

887837

Q9Y134
RNA helicase

1

11

High-throughput

0.445

High

887790

Q7JX41
Geminin

1

0

High-throughput

0.426

High

887793

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.426

High

887804

Q9VC93
Exosome complex exonuclease RRP44

1

0

High-throughput

0.426

High

887821

RUXG
Probable small nuclear ribonucleoprotein G

1

0

High-throughput

0.426

High

887788

Q29QQ9
Ribosomal RNA-processing protein 42

1

1

High-throughput

0.407

High

887791

Q7K0L8
FLICE-associated huge protein, isoform A

1

1

High-throughput

0.407

High

887792

Q7K1Q7
Ribosome assembly factor mrt4

1

2

High-throughput

0.407

High

887795

NHP2
H/ACA ribonucleoprotein complex subunit 2

1

2

High-throughput

0.407

High

887799

RU2A
Probable U2 small nuclear ribonucleoprotein A'

1

3

High-throughput

0.407

High

887801

SRRT
Serrate RNA effector molecule homolog

1

1

High-throughput

0.407

High

887802

Q9VB04
Protein CASC3

1

2

High-throughput

0.407

High

887809

Q9VKW8
U6 snRNA-associated Sm-like protein LSm4

1

1

High-throughput

0.407

High

887810

Q9VM14
dihydrolipoyllysine-residue acetyltransferase

1

1

High-throughput

0.407

High

887811

RM10
Large ribosomal subunit protein uL10m

1

1

High-throughput

0.407

High

887812

Q9VPM0
GH06023p

1

1

High-throughput

0.407

High

887816

QTRT2
Queuine tRNA-ribosyltransferase accessory subunit 2

1

1

High-throughput

0.407

High

887817

RM39
Large ribosomal subunit protein mL39

1

1

High-throughput

0.407

High

887822

IF5
Eukaryotic translation initiation factor 5

1

1

High-throughput

0.407

High

887824

Q9VYT3
FI23714p1

1

2

High-throughput

0.407

High

887826

THUM1
THUMP domain-containing protein 1 homolog

1

1

High-throughput

0.407

High

887827

SAHH2
Adenosylhomocysteinase-like 1

1

1

High-throughput

0.407

High

887828

Q9W108
FI01540p

1

4

High-throughput

0.407

High

887833

Q9W4J4
GM14292p

1

1

High-throughput

0.407

High

875521

PTPS
6-pyruvoyl tetrahydrobiopterin synthase

1

0

High-throughput

0.232

Low

887806

Q9VHT5
Large ribosomal subunit protein uL1m

1

0

High-throughput

0.232

Low

887820

Q9VVM7
IP21091p

1

0

High-throughput

0.232

Low

887830

Q9W1M9
Exosome complex component RRP4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025