HitPredict

Interactor 1: UB2G2 (P60604)
Ubiquitin-conjugating enzyme E2 G2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G2) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2)
Gene: UBE2G2

Interactor 2: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25515538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 165 Hs			1 542
+	Hs
		895947 UB2D3_HUMAN (4-164): 1.16e-71: 213: 34.78		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		849492 UB2D1_HUMAN (4-164): 3.3e-73: 217: 36.03		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		919912 UB2D2_HUMAN (4-164): 5.65e-73: 217: 36.03		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		895959 UB2D3_HUMAN (4-164): 1.16e-71: 213: 34.78		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		1174552 UB2R2_HUMAN (4-158): 9.21e-45: 149: 50.00		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		828051 UB2R1_HUMAN (4-159): 1.54e-43: 145: 49.08		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		1174554 UB2R2_HUMAN (4-158): 9.21e-45: 149: 50.00		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Dm
		218245 UBCD1_DROME (4-164): 1.2e-72: 216: 34.78		O44382_DROME (320-537): 1.23e-57: 202: 30.32
+	Hs
		827995 UB2R1_HUMAN (4-159): 1.54e-43: 145: 49.08		FBXW7_HUMAN (18-424): 1.12e-72: 246: 20.29
+	Hs
		1163056 UB2D4_HUMAN (4-164): 2.75e-74: 220: 36.03		TRAF7_HUMAN (353-522): 1.18e-28: 122: 27.17
+	Hs
		849344 UB2D1_HUMAN (4-164): 3.3e-73: 217: 36.03		TRAF7_HUMAN (353-522): 1.18e-28: 122: 27.17
+	Hs
		919755 UB2D2_HUMAN (4-164): 5.65e-73: 217: 36.03		TRAF7_HUMAN (353-522): 1.18e-28: 122: 27.17
+	Hs
		919901 UB2D2_HUMAN (4-164): 5.65e-73: 217: 36.03		FBXW2_HUMAN (357-517): 4.14e-24: 106: 27.59
+	Sc
		759317 UBC7_YEAST (1-165): 3.95e-70: 210: 62.42		MET30_YEAST (429-535): 5.29e-19: 92.7: 26.85
+	At
		189083 UBC28_ARATH (4-164): 1.18e-73: 218: 36.03		GBLPA_ARATH (246-470): 1e-11: 68.2: 24.81
+	At
		188984 UBC9_ARATH (4-164): 8.38e-73: 217: 36.03		GBLPA_ARATH (246-470): 1e-11: 68.2: 24.81
+	At
		188985 UBC10_ARATH (4-164): 1.29e-72: 216: 35.40		GBLPA_ARATH (246-470): 1e-11: 68.2: 24.81
+	At
		188986 UBC11_ARATH (4-164): 1.85e-72: 216: 35.40		GBLPA_ARATH (246-470): 1e-11: 68.2: 24.81
+	Hs
		827922 UB2R1_HUMAN (4-159): 1.54e-43: 145: 49.08		TBL3_HUMAN (237-531): 4.06e-24: 108: 24.46
+	Hs
		828056 UB2R1_HUMAN (4-159): 1.54e-43: 145: 49.08		FBXW2_HUMAN (357-517): 4.14e-24: 106: 27.59