HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: ENAH (Q8N8S7)
Protein enabled homolog
Gene: ENAH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0030027 - lamellipodium and 1 others more... GO:0045202 - synapse
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 591
+	Hs
		1122440 ACTBL_HUMAN (2-375): 0: 735: 91.71		HOME1_HUMAN (1-285): 2.84e-39: 149: 15.64
+	Hs
		929926 ACTG_HUMAN (1-375): 0: 601: 98.93		ENAH_HUMAN (1-591): 2.13e-77: 258: 100.00
+	Hs
		932262 ACTC_HUMAN (2-375): 0: 592: 94.12		ENAH_HUMAN (1-591): 2.13e-77: 258: 100.00
+	Hs
		357 ACTB_HUMAN (1-375): 0: 603: 100.00		A0A075B6E5_HUMAN (1-162): 2.4e-58: 196: 74.69
+	Hs
		358 ACTG_HUMAN (1-375): 0: 601: 98.93		A0A075B6E5_HUMAN (1-162): 2.4e-58: 196: 74.69
+	Hs
		891932 ACTB_HUMAN (1-375): 0: 603: 100.00		CTTB2_HUMAN (87-571): 1.34e-43: 169: 13.08
+	Hs
		891877 ACTB_HUMAN (1-375): 0: 603: 100.00		HOME1_HUMAN (1-285): 2.84e-39: 149: 15.64
+	Hs
		930047 ACTG_HUMAN (1-375): 0: 601: 98.93		TNIK_HUMAN (129-587): 5.09e-30: 128: 17.86
+	Hs
		930044 ACTG_HUMAN (1-375): 0: 601: 98.93		EVL_HUMAN (1-374): 7.41e-27: 115: 32.71
+	Hs
		892049 ACTB_HUMAN (1-375): 0: 603: 100.00		MYO10_HUMAN (182-480): 4.53e-25: 112: 14.15
+	Hs
		930011 ACTG_HUMAN (1-375): 0: 601: 98.93		MYO10_HUMAN (182-480): 4.53e-25: 112: 14.15
+	Hs
		840448 ACTB_HUMAN (1-375): 0: 603: 100.00		VASP_HUMAN (263-590): 7.68e-20: 93.6: 29.18
+	Hs
		840454 ACTG_HUMAN (1-375): 0: 601: 98.93		VASP_HUMAN (263-590): 7.68e-20: 93.6: 29.18
+	Hs
		840455 ACTC_HUMAN (2-375): 0: 592: 94.12		VASP_HUMAN (263-590): 7.68e-20: 93.6: 29.18
+	Hs
		892089 ACTB_HUMAN (1-375): 0: 603: 100.00		SWP70_HUMAN (84-269): 5.97e-14: 76.9: 25.00