HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: SPTB2 (Q01082)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)
Gene: SPTBN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030036 - actin cytoskeleton organization GO:0070062 - extracellular exosome GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 2364
+	Hs
		925201 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		SPTB2_HUMAN (1-2364): 0: 751: 100.00
+	Hs
		545327 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		SPTB2_HUMAN (1-2364): 0: 751: 100.00
+	Hs
		963416 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		SPTB2_HUMAN (1-2364): 0: 751: 100.00
+	Hs
		297823 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		K0754_HUMAN (210-1343): 2.52e-36: 154: 15.07
+	Hs
		297812 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		K0754_HUMAN (210-1343): 2.52e-36: 154: 15.07
+	Hs
		297840 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		K0754_HUMAN (210-1343): 2.52e-36: 154: 15.07
+	Hs
		297819 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		K0754_HUMAN (210-1343): 2.52e-36: 154: 15.07
+	Hs
		925215 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		DYST_HUMAN (537-1421): 8.42e-22: 106: 12.00
+	Hs
		545334 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		DYST_HUMAN (537-1421): 8.42e-22: 106: 12.00
+	Hs
		925265 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Hs
		809099 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		UTRN_HUMAN (212-2073): 1e-17: 93.2: 10.02
+	Hs
		545364 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Hs
		1045519 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Hs
		545254 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		UTRN_HUMAN (212-2073): 1e-17: 93.2: 10.02
+	Hs
		809170 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		UTRN_HUMAN (212-2073): 1e-17: 93.2: 10.02
+	Hs
		892360 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Hs
		809091 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		UTRN_HUMAN (212-2073): 1e-17: 93.2: 10.02
+	Hs
		164599 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		SPTN2_HUMAN (1661-2338): 1.76e-11: 72.4: 15.10
+	Hs
		164665 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		SPTN2_HUMAN (1661-2338): 1.76e-11: 72.4: 15.10
+	Hs
		164589 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		SPTN2_HUMAN (1661-2338): 1.76e-11: 72.4: 15.10