HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: S11IP (Q8N1F8)
Serine/threonine-protein kinase 11-interacting protein (LKB1-interacting protein 1)
Gene: STK11IP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1088
+	Hs
		545490 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		S11IP_HUMAN (1-1088): 0: 1106: 100.00
+	Dm
		776889 RAC1_DROME (1-192): 2.16e-81: 241: 89.06		SCRIB_DROME (9-528): 2.09e-62: 235: 16.57
+	Hs
		925419 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		LRC8A_HUMAN (11-419): 5.08e-36: 149: 15.44
+	Hs
		545486 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		LRC8A_HUMAN (11-419): 5.08e-36: 149: 15.44
+	Hs
		1219415 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		LRC8A_HUMAN (11-419): 5.08e-36: 149: 15.44
+	Hs
		892474 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		LRC8A_HUMAN (11-419): 5.08e-36: 149: 15.44
+	Hs
		925539 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		ERBIN_HUMAN (166-574): 3.23e-29: 128: 12.12
+	Hs
		545571 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		ERBIN_HUMAN (166-574): 3.23e-29: 128: 12.12
+	Hs
		1301445 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		ERBIN_HUMAN (166-574): 3.23e-29: 128: 12.12
+	Hs
		892548 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		ERBIN_HUMAN (166-574): 3.23e-29: 128: 12.12
+	Hs
		925273 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		SCRIB_HUMAN (1-174): 1.23e-15: 84.4: 14.50
+	Hs
		925580 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		LGR4_HUMAN (98-296): 3.23e-13: 76.3: 27.18
+	Hs
		545370 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		SCRIB_HUMAN (1-174): 1.23e-15: 84.4: 14.50
+	Hs
		1050061 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		SCRIB_HUMAN (1-174): 1.23e-15: 84.4: 14.50
+	Hs
		925746 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		NISCH_HUMAN (3-145): 2.91e-12: 73.3: 14.77
+	Hs
		892367 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		SCRIB_HUMAN (1-174): 1.23e-15: 84.4: 14.50
+	Hs
		1315147 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		LGR4_HUMAN (98-296): 3.23e-13: 76.3: 27.18
+	Hs
		545706 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		NISCH_HUMAN (3-145): 2.91e-12: 73.3: 14.77
+	Hs
		1330998 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		NISCH_HUMAN (3-145): 2.91e-12: 73.3: 14.77
+	Hs
		892569 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		LGR4_HUMAN (98-296): 3.23e-13: 76.3: 27.18