Protein: PYR1
Multifunctional protein CAD (Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase) [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Glutamine amidotransferase (GATase) (GLNase) (EC 3.5.1.2); Ammonium-dependent carbamoyl phosphate synthase (CPS) (CPSase) (EC 6.3.4.16); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]

Gene: PYR1, Cad
Organism: Mus musculus
Interactions: 19
UniProt ID: B2RQC6

Gene Ontology (top 5):
GO:0001889 - liver development
GO:0002134 - UTP binding
GO:0004070 - aspartate carbamoyltransferase activity
GO:0004087 - carbamoyl-phosphate synthase (ammonia) activity
GO:0004088 - carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

73894

PO5F1
POU domain, class 5, transcription factor 1

1

1

High-throughput

0.536

High

73896

TNIK
Traf2 and NCK-interacting protein kinase

1

7

High-throughput

0.536

High

73899

FXR1
RNA-binding protein FXR1

1

4

High-throughput

0.536

High

73901

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

3

High-throughput

0.536

High

73903

MYOME
Myomegalin

1

2

High-throughput

0.536

High

73909

TSC1
Hamartin

1

2

High-throughput

0.536

High

73911

NPHP1
Nephrocystin-1

1

0

High-throughput

0.513

High

73898

PPP5
Serine/threonine-protein phosphatase 5

1

6

High-throughput

0.479

High

73902

FACD2
Fanconi anemia group D2 protein homolog

1

3

High-throughput

0.479

High

73905

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

4

High-throughput

0.479

High

73907

FOXP3
Forkhead box protein P3

1

1

High-throughput

0.479

High

73908

RN138
E3 ubiquitin-protein ligase RNF138

1

2

Small-scale

0.479

High

73910

CAF1A
Chromatin assembly factor 1 subunit A

1

1

High-throughput

0.479

High

73900

TEDC2
Tubulin epsilon and delta complex protein 2

1

0

High-throughput

0.458

High

73893

MET
Hepatocyte growth factor receptor

1

5

High-throughput

0.445

High

73906

FTM
Protein fantom

1

5

High-throughput

0.445

High

73904

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

7

High-throughput

0.437

High

73895

HMGA2
High mobility group protein HMGI-C

1

0

High-throughput

0.426

High

73897

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.426

High


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Last updated: 11Aug2025