HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: ANS1A (Q92625)
Ankyrin repeat and SAM domain-containing protein 1A (Odin)
Gene: ANKS1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	GO:0005829 - cytosol GO:0043005 - neuron projection
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1134
+	Hs
		925491 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		ANS1A_HUMAN (1-1134): 0: 792: 100.00
+	Mm
		892714 RAC3_MOUSE (1-192): 5.54e-79: 235: 100.00		ANS1B_MOUSE (1-1133): 0: 621: 33.57
+	Hs
		900638 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		ANS1B_HUMAN (1-1101): 0: 593: 33.52
+	Hs
		925476 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		CSKI2_HUMAN (1-592): 3.95e-69: 255: 24.71
+	Hs
		1263389 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		CSKI2_HUMAN (1-592): 3.95e-69: 255: 24.71
+	Hs
		892514 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		CSKI2_HUMAN (1-592): 3.95e-69: 255: 24.71
+	Hs
		925723 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		KDIS_HUMAN (121-538): 2.01e-56: 216: 15.20
+	Hs
		545696 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		KDIS_HUMAN (121-538): 2.01e-56: 216: 15.20
+	Hs
		1330985 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		KDIS_HUMAN (121-538): 2.01e-56: 216: 15.20
+	Hs
		892676 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		KDIS_HUMAN (121-538): 2.01e-56: 216: 15.20
+	Hs
		951454 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		KDIS_HUMAN (121-538): 2.01e-56: 216: 15.20
+	Hs
		894580 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		KDIS_HUMAN (121-538): 2.01e-56: 216: 15.20
+	Hs
		901042 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		KDIS_HUMAN (121-538): 2.01e-56: 216: 15.20
+	Hs
		925238 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		ANK3_HUMAN (183-812): 9.9e-38: 157: 12.04
+	Hs
		925204 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		ANK2_HUMAN (180-837): 1.86e-34: 146: 13.55
+	Hs
		950953 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		ANK3_HUMAN (183-812): 9.9e-38: 157: 12.04
+	Hs
		893947 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		ANK3_HUMAN (183-812): 9.9e-38: 157: 12.04
+	Hs
		900423 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		ANK3_HUMAN (183-812): 9.9e-38: 157: 12.04
+	Hs
		900896 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		Q9H4D1_HUMAN (60-245): 4.58e-19: 95.1: 38.17
+	Hs
		883465 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		RIPK4_HUMAN (60-245): 1.22e-18: 94: 37.63