HitPredict

Interactor 1: ACTN2 (P35609)
Alpha-actinin-2 (Alpha-actinin skeletal muscle isoform 2) (F-actin cross-linking protein)
Gene: ACTN2

Interactor 2: CLC4D (Q8WXI8)
C-type lectin domain family 4 member D (C-type lectin superfamily member 8) (C-type lectin-like receptor 6) (CLEC-6) (Dendritic cell-associated C-type lectin 3) (DC-associated C-type lectin 3) (Dectin-3) (CD antigen CD368)
Gene: CLEC4D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.523

Property	Details
Experiments	25910212
Identification Methods	two hybrid, two hybrid bait and prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 894 Hs			1 215
+	Hs
		521585 ACTN1_HUMAN (8-894): 0: 658: 79.48		CLC4D_HUMAN (1-215): 2.59e-71: 217: 100.00
+	Hs
		521636 ACTN1_HUMAN (8-894): 0: 658: 79.48		CLC4E_HUMAN (5-214): 6.42e-59: 186: 35.85
+	Hs
		211627 ACTN4_HUMAN (18-894): 0: 619: 77.89		CLC4D_HUMAN (1-215): 2.59e-71: 217: 100.00
+	Hs
		211690 ACTN4_HUMAN (18-894): 0: 619: 77.89		CLC4E_HUMAN (5-214): 6.42e-59: 186: 35.85
+	Hs
		164645 SPTN2_HUMAN (250-805): 1.17e-09: 64.7: 10.73		CLC4D_HUMAN (1-215): 2.59e-71: 217: 100.00
+	Hs
		506850 SPTB1_HUMAN (245-777): 2.92e-11: 69.7: 10.24		CLC4E_HUMAN (5-214): 6.42e-59: 186: 35.85
+	Hs
		164675 SPTN2_HUMAN (250-805): 1.17e-09: 64.7: 10.73		CLC4E_HUMAN (5-214): 6.42e-59: 186: 35.85