HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: ARHGQ (Q96DR7)
Rho guanine nucleotide exchange factor 26 (SH3 domain-containing guanine exchange factor)
Gene: ARHGEF26

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 32203420, 31871319
Identification Methods fluorescent resonance energy transfer, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~Ras, Ras~RhoGEF
Common GO terms GO:0005829 - cytosol
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 191
Hs

1 871
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024