HitPredict

Interactor 1: RAB2A (P61019)
Ras-related protein Rab-2A (EC 3.6.5.2)
Gene: RAB2A

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005765 - lysosomal membrane GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 212 Hs			1 1164
+	Hs
		914256 RB11A_HUMAN (3-212): 2.35e-83: 248: 46.67		TSC1_HUMAN (1-1164): 0: 725: 100.00
+	Hs
		591957 RAB4A_HUMAN (3-188): 6.91e-72: 219: 57.53		TSC1_HUMAN (1-1164): 0: 725: 100.00
+	Mm
		1265042 RAB14_MOUSE (3-211): 2.23e-83: 248: 58.85		TSC1_MOUSE (1-1164): 0: 695: 86.98
+	Hs
		1079935 RB11B_HUMAN (3-212): 1.54e-82: 246: 47.62		Q86WV8_HUMAN (1-343): 3.4e-177: 526: 100.00
+	Hs
		895077 RAB2A_HUMAN (1-212): 1.36e-87: 258: 100.00		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		895213 RAB2A_HUMAN (1-212): 1.36e-87: 258: 100.00		MY18A_HUMAN (461-1064): 4e-25: 115: 10.31
+	Hs
		254463 RAB2A_HUMAN (1-212): 1.36e-87: 258: 100.00		ROCK2_HUMAN (415-1038): 1.55e-24: 113: 11.27
+	Hs
		254466 RB11A_HUMAN (3-212): 2.35e-83: 248: 46.67		ROCK2_HUMAN (415-1038): 1.55e-24: 113: 11.27
+	Hs
		148636 RAB1A_HUMAN (3-212): 3.93e-84: 249: 45.24		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		149274 RAB1B_HUMAN (3-212): 7.6e-83: 246: 44.29		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		895123 RAB2A_HUMAN (1-212): 1.36e-87: 258: 100.00		MRCKA_HUMAN (278-842): 4.78e-17: 89.1: 8.78
+	Hs
		895066 RAB2A_HUMAN (1-212): 1.36e-87: 258: 100.00		ROCK1_HUMAN (433-926): 6.18e-15: 82.2: 12.00
+	Hs
		914124 RB11A_HUMAN (3-212): 2.35e-83: 248: 46.67		MRCKA_HUMAN (278-842): 4.78e-17: 89.1: 8.78
+	Hs
		914116 RB11A_HUMAN (3-212): 2.35e-83: 248: 46.67		CYTSB_HUMAN (740-1117): 1.86e-12: 74.1: 12.41
+	Hs
		591838 RAB4A_HUMAN (3-188): 6.91e-72: 219: 57.53		ROCK1_HUMAN (433-926): 6.18e-15: 82.2: 12.00