HitPredict

Interactor 1: CKS1 (P61024)
Cyclin-dependent kinases regulatory subunit 1 (CKS-1)
Gene: CKS1B

Interactor 2: PMYT1 (Q99640)
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)
Gene: PKMYT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	28514442, 33961781, 32707033
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CKS~Pkinase
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 79 Hs			1 499
+	Hs
		706809 CKS2_HUMAN (1-79): 5.68e-38: 122: 81.01		PMYT1_HUMAN (1-499): 3.82e-135: 401: 100.00
+	Hs
		625283 CKS1_HUMAN (1-79): 9.36e-40: 127: 100.00		CDK2_HUMAN (107-360): 2.87e-100: 305: 27.43
+	Hs
		625164 CKS2_HUMAN (1-79): 5.68e-38: 122: 81.01		CDK2_HUMAN (107-360): 2.87e-100: 305: 27.43
+	Sp
		428840 CKS1_SCHPO (4-71): 1.22e-30: 105: 50.65		WEE1_SCHPO (110-355): 1.27e-34: 140: 37.87
+	Sc
		594119 CKS1_YEAST (3-73): 3.34e-32: 110: 50.00		SWE1_YEAST (100-320): 1.08e-24: 110: 31.38
+	Hs
		895413 CKS1_HUMAN (1-79): 9.36e-40: 127: 100.00		CDK3_HUMAN (110-362): 3.53e-20: 92.8: 28.22
+	Hs
		706796 CKS2_HUMAN (1-79): 5.68e-38: 122: 81.01		CDK3_HUMAN (110-362): 3.53e-20: 92.8: 28.22