HitPredict

Interactor 1: CDK7 (P50613)
Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)
Gene: CDK7

Interactor 2: RB6I2 (Q8IUD2)
ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2)
Gene: ERC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 346 Hs			1 1116
+	Hs
		563005 CDK3_HUMAN (9-306): 8.07e-143: 407: 45.00		MYH6_HUMAN (339-1116): 9.15e-35: 147: 12.47
+	Hs
		1307164 CDK20_HUMAN (11-310): 1.24e-77: 243: 43.28		RB6I2_HUMAN (1-1116): 4.21e-87: 307: 100.00
+	Hs
		556845 CDK3_HUMAN (9-306): 8.07e-143: 407: 45.00		MYH1_HUMAN (2-633): 2.23e-28: 126: 11.93
+	Hs
		1025301 CDK3_HUMAN (9-306): 8.07e-143: 407: 45.00		MYH13_HUMAN (3-547): 3.56e-22: 105: 10.95
+	Hs
		667590 CDK2_HUMAN (9-307): 4.88e-150: 426: 43.85		MYH9_HUMAN (771-1116): 1.24e-15: 84.8: 10.12
+	Hs
		772679 CDK7_HUMAN (1-346): 3.12e-147: 420: 100.00		MYH9_HUMAN (771-1116): 1.24e-15: 84.8: 10.12
+	Hs
		1025300 CDK3_HUMAN (9-306): 8.07e-143: 407: 45.00		MYH2_HUMAN (736-1116): 4.65e-18: 92.5: 15.10
+	Hs
		667591 CDK2_HUMAN (9-307): 4.88e-150: 426: 43.85		MYH10_HUMAN (2-407): 8.75e-12: 72.1: 9.98
+	Hs
		773129 CDK7_HUMAN (1-346): 3.12e-147: 420: 100.00		MYH10_HUMAN (2-407): 8.75e-12: 72.1: 9.98
+	Hs
		563043 CDK2_HUMAN (9-307): 4.88e-150: 426: 43.85		MYH8_HUMAN (1-326): 3.46e-09: 63.6: 9.51
+	Hs
		667955 CDK2_HUMAN (9-307): 4.88e-150: 426: 43.85		MY18A_HUMAN (439-976): 3.59e-09: 63.5: 18.73
+	Hs
		1025302 CDK3_HUMAN (9-306): 8.07e-143: 407: 45.00		MYH15_HUMAN (120-590): 1.47e-13: 77.9: 12.74
+	Hs
		535930 CDK3_HUMAN (9-306): 8.07e-143: 407: 45.00		MYH3_HUMAN (690-1116): 1.51e-13: 77.8: 12.33
+	Hs
		156845 CDK1_HUMAN (9-298): 6.72e-135: 387: 43.00		CTRO_HUMAN (156-758): 7.78e-19: 95.1: 14.09
+	Hs
		556914 CDK3_HUMAN (9-306): 8.07e-143: 407: 45.00		MYH7_HUMAN (1-318): 3.84e-10: 66.7: 7.55
+	Hs
		563048 CDK3_HUMAN (9-306): 8.07e-143: 407: 45.00		MYH8_HUMAN (1-326): 3.46e-09: 63.6: 9.51