Protein: CDK20
Cyclin-dependent kinase 20 (EC 2.7.11.22) (CDK-activating kinase p42) (CAK-kinase p42) (Cell cycle-related kinase) (Cell division protein kinase 20) (Cyclin-dependent protein kinase H) (Cyclin-kinase-activating kinase p42)

Gene: CDK20
Organism: Homo sapiens
Interactions: 118
UniProt ID: Q8IZL9

Gene Ontology (top 5):
GO:0001843 - neural tube closure
GO:0004674 - protein serine/threonine kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

897337

CDK7
Cyclin-dependent kinase 7

3

16

High-throughput

0.861

High

1025485

CDK5
Cyclin-dependent kinase 5

3

15

High-throughput

0.861

High

1125530

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

5

11

Small-scale

0.827

High

1316647

CILK1
Serine/threonine-protein kinase ICK

1

17

Small-scale

0.724

High

908706

CCNH
Cyclin-H

1

20

Small-scale

0.713

High

995129

CSK2B
Casein kinase II subunit beta

1

1

Small-scale

0.713

High

290333

KS6A4
Ribosomal protein S6 kinase alpha-4

1

8

High-throughput

0.691

High

461690

HS90A
Heat shock protein HSP 90-alpha

1

19

High-throughput

0.691

High

463155

YES
Tyrosine-protein kinase Yes

1

12

High-throughput

0.691

High

468581

HS90B
Heat shock protein HSP 90-beta

1

19

High-throughput

0.691

High

858682

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

20

High-throughput

0.691

High

1105995

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

11

High-throughput

0.691

High

1316621

PASK
PAS domain-containing serine/threonine-protein kinase

1

6

High-throughput

0.691

High

1316622

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

6

High-throughput

0.691

High

1316638

CDK12
Cyclin-dependent kinase 12

1

17

High-throughput

0.691

High

1316619

FOXJ1
Forkhead box protein J1

4

3

High-throughput

0.691

High

635002

MAK
Serine/threonine-protein kinase MAK

1

17

Small-scale

0.665

High

1025822

BORG5
Cdc42 effector protein 1

2

0

Small-scale

0.660

High

667930

CDK2
Cyclin-dependent kinase 2

1

17

Small-scale

0.647

High

1316652

CFA20
Cilia- and flagella-associated protein 20

3

0

High-throughput

0.646

High

1316644

CHIP
E3 ubiquitin-protein ligase CHIP

2

5

High-throughput

0.628

High

1158417

CDC37
Hsp90 co-chaperone Cdc37

1

6

High-throughput

0.618

High

401126

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

15

High-throughput

0.618

High

1194210

LARP7
La-related protein 7

1

14

High-throughput

0.618

High

1141584

OZF
Zinc finger protein OZF

1

0

High-throughput

0.586

High

1201990

H90B4
Putative heat shock protein HSP 90-beta 4

1

19

High-throughput

0.575

High

1312319

MIRO1
Mitochondrial Rho GTPase 1

1

10

Small-scale

0.553

High

1253965

RBPS2
RNA-binding protein with multiple splicing 2

1

0

High-throughput

0.546

High

420611

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

3

High-throughput

0.536

High

457545

TBB5
Tubulin beta chain

1

6

High-throughput

0.536

High

520913

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

3

High-throughput

0.536

High

537493

HSP7C
Heat shock cognate 71 kDa protein

1

11

High-throughput

0.536

High

565970

EF2
Elongation factor 2

1

7

High-throughput

0.536

High

600857

HSP76
Heat shock 70 kDa protein 6

1

11

High-throughput

0.536

High

697585

PYR1
Multifunctional protein CAD

1

4

High-throughput

0.536

High

723018

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

4

High-throughput

0.536

High

731452

STIP1
Stress-induced-phosphoprotein 1

1

5

High-throughput

0.536

High

887690

PSB2
Proteasome subunit beta type-2

1

5

High-throughput

0.536

High

930985

HSP72
Heat shock-related 70 kDa protein 2

1

11

High-throughput

0.536

High

975454

PRS10
26S proteasome regulatory subunit 10B

1

6

High-throughput

0.536

High

997025

TBA4A
Tubulin alpha-4A chain

1

7

High-throughput

0.536

High

1066388

RBBP4
Histone-binding protein RBBP4

1

2

High-throughput

0.536

High

1108601

TBB3
Tubulin beta-3 chain

1

6

High-throughput

0.536

High

1130100

SMC1A
Structural maintenance of chromosomes protein 1A

1

11

High-throughput

0.536

High

1206989

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

1

High-throughput

0.536

High

1245042

TRI65
E3 ubiquitin-protein ligase TRIM65

1

7

High-throughput

0.536

High

1259334

TBA1A
Tubulin alpha-1A chain

1

9

High-throughput

0.536

High

1272831

DHX32
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32

1

4

High-throughput

0.536

High

1316608

RPTOR
Regulatory-associated protein of mTOR

1

8

High-throughput

0.536

High

1316612

PCAT1
Lysophosphatidylcholine acyltransferase 1

1

5

High-throughput

0.536

High

1316613

NEDD1
Protein NEDD1

1

4

High-throughput

0.536

High

1316618

RAD50
DNA repair protein RAD50

1

19

High-throughput

0.536

High

1316623

TBA1C
Tubulin alpha-1C chain

1

9

High-throughput

0.536

High

1316624

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

1

High-throughput

0.536

High

1316626

TCAB1
Telomerase Cajal body protein 1

1

12

High-throughput

0.536

High

1316627

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.536

High

1316632

ESRP2
Epithelial splicing regulatory protein 2

1

9

High-throughput

0.536

High

1316634

PYRG2
CTP synthase 2

1

2

High-throughput

0.536

High

1316637

RNF12
E3 ubiquitin-protein ligase RLIM

1

4

High-throughput

0.536

High

1316642

BAG5
BAG family molecular chaperone regulator 5

1

1

High-throughput

0.536

High

1316649

NOP58
Nucleolar protein 58

1

2

High-throughput

0.536

High

1162682

UBE2S
Ubiquitin-conjugating enzyme E2 S

1

4

High-throughput

0.515

High

885591

PRI2
DNA primase large subunit

1

0

High-throughput

0.513

High

932485

KAD2
Adenylate kinase 2, mitochondrial

1

0

High-throughput

0.513

High

1185198

EDRF1
Erythroid differentiation-related factor 1

1

0

High-throughput

0.513

High

1252805

NFXL1
NF-X1-type zinc finger protein NFXL1

1

0

High-throughput

0.513

High

1316611

EFNMT
eEF1A lysine and N-terminal methyltransferase

1

0

High-throughput

0.513

High

1316625

NTPCR
Cancer-related nucleoside-triphosphatase

1

0

High-throughput

0.513

High

1316639

CPNE7
Copine-7

1

0

High-throughput

0.513

High

916686

PPP5
Serine/threonine-protein phosphatase 5

1

11

Small-scale

0.501

High

1316628

TRIM2
Tripartite motif-containing protein 2

1

8

High-throughput

0.494

High

423803

APOD
Apolipoprotein D

1

1

High-throughput

0.489

High

688588

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

1

High-throughput

0.489

High

698869

CALX
Calnexin

1

3

High-throughput

0.489

High

848046

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

1

High-throughput

0.489

High

1307164

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

16

High-throughput

0.489

High

1316609

S11IP
Serine/threonine-protein kinase 11-interacting protein

1

2

High-throughput

0.489

High

1316617

GCN1
Stalled ribosome sensor GCN1

1

8

High-throughput

0.489

High

1316633

WDR6
tRNA

1

15

High-throughput

0.489

High

1316641

GGT7
Glutathione hydrolase 7

1

1

High-throughput

0.489

High

1316646

HPS5
BLOC-2 complex member HPS5

1

1

High-throughput

0.489

High

1288855

GTD2A
General transcription factor II-I repeat domain-containing protein 2A

1

1

Small-scale

0.481

High

324977

HEXI1
Protein HEXIM1

1

4

High-throughput

0.479

High

701187

PSB5
Proteasome subunit beta type-5

1

5

High-throughput

0.479

High

938588

PSA
Puromycin-sensitive aminopeptidase

1

1

Small-scale

0.479

High

1109883

HDAC1
Histone deacetylase 1

1

3

High-throughput

0.479

High

1121454

KEAP1
Kelch-like ECH-associated protein 1

1

1

Small-scale

0.479

High

1316640

XPO7
Exportin-7

1

2

High-throughput

0.479

High

1316643

FZR1
Fizzy-related protein homolog

1

17

High-throughput

0.479

High

1316645

MAGD2
Melanoma-associated antigen D2

1

1

High-throughput

0.479

High

1316636

PANK4
4'-phosphopantetheine phosphatase

1

0

Small-scale

0.460

High

871789

RFX3
Transcription factor RFX3

1

0

High-throughput

0.458

High

1131765

LBR
Delta(14)-sterol reductase LBR

1

0

Small-scale

0.458

High

648196

NDKB
Nucleoside diphosphate kinase B

1

3

High-throughput

0.445

High

967493

RS7
Small ribosomal subunit protein eS7

1

2

High-throughput

0.445

High

283909

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

1

Small-scale

0.437

High

58864

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

6

High-throughput

0.407

High

903731

SSRD
Translocon-associated protein subunit delta

1

1

High-throughput

0.407

High

937554

CAD11
Cadherin-11

1

2

High-throughput

0.407

High

1316616

SL9A6
Sodium/hydrogen exchanger 6

3

0

High-throughput

0.345

High

124403

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.279

Low

156151

TRAD1
TRAF-type zinc finger domain-containing protein 1

1

0

High-throughput

0.279

Low

391341

FRIL
Ferritin light chain

1

0

High-throughput

0.279

Low

1017790

CCZ1B
Vacuolar fusion protein CCZ1 homolog B

1

0

High-throughput

0.279

Low

1180650

AP5B1
AP-5 complex subunit beta-1

1

0

High-throughput

0.279

Low

1257731

VP13C
Intermembrane lipid transfer protein VPS13C

1

0

High-throughput

0.279

Low

1316615

MADD
MAP kinase-activating death domain protein

1

0

High-throughput

0.279

Low

1316620

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.279

Low

1316629

TNG6
Transport and Golgi organization protein 6 homolog

1

0

High-throughput

0.279

Low

1316631

TRABD
TraB domain-containing protein

1

0

High-throughput

0.279

Low

1316635

T11L1
T-complex protein 11-like protein 1

1

0

High-throughput

0.279

Low

1316648

NEUR3
Sialidase-3

1

0

High-throughput

0.279

Low

1316650

MTO1
5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial

1

0

High-throughput

0.279

Low

1316651

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

0

High-throughput

0.279

Low

1316614

ACMSD
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase

1

0

High-throughput

0.269

Low

336988

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

Small-scale

0.249

Low

1316630

XYLT2
Xylosyltransferase 2

1

0

High-throughput

0.249

Low

1316610

VW5B2
von Willebrand factor A domain-containing protein 5B2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025