HitPredict

Interactor 1: RAP1B (P61224)
Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B)
Gene: RAP1B

Interactor 2: RIN3 (Q8TB24)
Ras and Rab interactor 3 (Ras interaction/interference protein 3)
Gene: RIN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	32552912
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~VPS9
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 184 Hs			1 985
+	Hs
		1137131 Q5U0I6_HUMAN (4-183): 4.68e-73: 220: 31.49		RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00
+	Hs
		918912 RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49		RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00
+	Hs
		72912 B4DMN1_HUMAN (4-178): 7.87e-71: 216: 28.98		RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00
+	Ce
		104435 RAC1_CAEEL (1-184): 8.89e-69: 209: 27.55		G5EBS9_CAEEL (477-958): 1.73e-56: 213: 20.04
+	Hs
		166043 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77
+	Hs
		914438 RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98		RABX5_HUMAN (548-876): 7.79e-51: 189: 15.32
+	Hs
		349717 RASH_HUMAN (1-167): 1.22e-55: 175: 57.49		RABX5_HUMAN (548-876): 7.79e-51: 189: 15.32
+	Hs
		349534 RASH_HUMAN (1-167): 1.22e-55: 175: 57.49		RIN2_HUMAN (28-376): 3.27e-39: 159: 28.49
+	Hs
		348831 RASN_HUMAN (1-167): 5.03e-54: 171: 56.89		RIN2_HUMAN (28-376): 3.27e-39: 159: 28.49
+	Dm
		332205 O96692_DROME (1-166): 2.56e-60: 187: 60.24		SPRI_DROME (34-706): 2.23e-33: 142: 16.72
+	Hs
		297823 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		K0754_HUMAN (6-390): 5.17e-23: 108: 12.47
+	Ce
		105104 RAC1_CAEEL (1-184): 8.89e-69: 209: 27.55		G5ECF0_CAEEL (17-239): 1.52e-22: 106: 22.27
+	Hs
		897983 RAP2B_HUMAN (1-184): 1.46e-65: 200: 61.41		RIN1_HUMAN (6-327): 3.07e-21: 101: 26.32
+	Hs
		297806 RASK_HUMAN (1-167): 6.26e-55: 174: 57.49		K0754_HUMAN (6-390): 5.17e-23: 108: 12.47
+	Hs
		297805 RASN_HUMAN (1-167): 5.03e-54: 171: 56.89		K0754_HUMAN (6-390): 5.17e-23: 108: 12.47
+	Mm
		1142563 RASH_MOUSE (1-167): 1.22e-55: 175: 57.49		RIN1_MOUSE (19-305): 1.31e-21: 102: 25.50
+	Hs
		349304 RASH_HUMAN (1-167): 1.22e-55: 175: 57.49		RIN1_HUMAN (6-327): 3.07e-21: 101: 26.32
+	Hs
		350154 RASK_HUMAN (1-167): 6.26e-55: 174: 57.49		RIN1_HUMAN (6-327): 3.07e-21: 101: 26.32
+	Hs
		348653 RASN_HUMAN (1-167): 5.03e-54: 171: 56.89		RIN1_HUMAN (6-327): 3.07e-21: 101: 26.32
+	Hs
		203195 RASK_HUMAN (1-167): 6.26e-55: 174: 57.49		SYNJ1_HUMAN (311-736): 7.31e-12: 71.8: 11.24