HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019901 - protein kinase binding GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 540
+	Hs
		951111 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00
+	Hs
		894165 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00
+	Hs
		545467 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00
+	Mm
		925811 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		MAVS_MOUSE (1-538): 5.1e-46: 170: 47.68
+	Hs
		297820 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		K0754_HUMAN (43-539): 5.17e-38: 151: 11.24
+	Hs
		297823 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		K0754_HUMAN (43-539): 5.17e-38: 151: 11.24
+	Hs
		297809 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		K0754_HUMAN (43-539): 5.17e-38: 151: 11.24
+	Hs
		297827 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		K0754_HUMAN (43-539): 5.17e-38: 151: 11.24
+	Hs
		297812 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		K0754_HUMAN (43-539): 5.17e-38: 151: 11.24
+	Hs
		297819 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		K0754_HUMAN (43-539): 5.17e-38: 151: 11.24
+	Hs
		925397 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Hs
		925724 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ASAP1_HUMAN (95-423): 4.61e-23: 105: 13.43
+	Ce
		136793 RAC1_CAEEL (1-193): 2.07e-80: 238: 55.44		UNC89_CAEEL (169-513): 1.01e-19: 95.6: 12.29
+	Hs
		925387 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MICA3_HUMAN (68-506): 7.25e-20: 96: 12.82
+	Ce
		104464 G5EBV3_CAEEL (2-193): 1.08e-77: 232: 50.52		UNC89_CAEEL (169-513): 1.01e-19: 95.6: 12.29
+	Ce
		136800 RHO1_CAEEL (1-192): 2.25e-75: 226: 85.94		UNC89_CAEEL (169-513): 1.01e-19: 95.6: 12.29
+	Hs
		892450 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		MICA3_HUMAN (68-506): 7.25e-20: 96: 12.82
+	Ce
		136794 CDC42_CAEEL (1-193): 2.41e-74: 223: 50.78		UNC89_CAEEL (169-513): 1.01e-19: 95.6: 12.29
+	Hs
		195972 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PLXB1_HUMAN (78-332): 1.47e-10: 66.3: 19.62
+	Hs
		867087 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		SC24C_HUMAN (116-429): 9.64e-11: 66.7: 15.43