HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: BRK1 (Q8WUW1)
Protein BRICK1 (BRK1)
Gene: BRK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0030027 - lamellipodium GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 75
+	Hs
		925471 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		BRK1_HUMAN (1-75): 1.59e-36: 119: 100.00
+	Hs
		436430 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		BRK1_HUMAN (1-75): 1.59e-36: 119: 100.00
+	Hs
		894253 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		BRK1_HUMAN (1-75): 1.59e-36: 119: 100.00
+	Hs
		545524 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		BRK1_HUMAN (1-75): 1.59e-36: 119: 100.00
+	Hs
		892508 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		BRK1_HUMAN (1-75): 1.59e-36: 119: 100.00