HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: PLCA (Q99943)
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 1) (1-AGP acyltransferase 1) (1-AGPAT 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha) (Protein G15)
Gene: AGPAT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 31871319
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 283
+	Hs
		900704 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PCAT1_HUMAN (8-281): 6.41e-69: 224: 16.84
+	Hs
		900625 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PCAT2_HUMAN (9-281): 3.32e-68: 222: 17.99
+	Hs
		925447 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PCAT1_HUMAN (8-281): 6.41e-69: 224: 16.84
+	Hs
		436412 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		PCAT1_HUMAN (8-281): 6.41e-69: 224: 16.84
+	Hs
		951167 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		PCAT1_HUMAN (8-281): 6.41e-69: 224: 16.84
+	Hs
		894225 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		PCAT1_HUMAN (8-281): 6.41e-69: 224: 16.84
+	Hs
		900645 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		GPAT4_HUMAN (8-278): 9.16e-65: 211: 17.65
+	Hs
		915841 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		PCAT1_HUMAN (8-281): 6.41e-69: 224: 16.84
+	Hs
		436381 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		GPAT4_HUMAN (8-278): 9.16e-65: 211: 17.65
+	Hs
		951123 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		GPAT4_HUMAN (8-278): 9.16e-65: 211: 17.65
+	Hs
		894173 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		GPAT4_HUMAN (8-278): 9.16e-65: 211: 17.65
+	Hs
		900541 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		GPAT3_HUMAN (8-278): 3.48e-61: 201: 17.65
+	Hs
		545473 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		GPAT4_HUMAN (8-278): 9.16e-65: 211: 17.65
+	Hs
		120546 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		PCAT1_HUMAN (8-281): 6.41e-69: 224: 16.84
+	Hs
		892460 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		GPAT4_HUMAN (8-278): 9.16e-65: 211: 17.65
+	Hs
		120513 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		GPAT4_HUMAN (8-278): 9.16e-65: 211: 17.65