HitPredict

Interactor 1: RND3 (P61587)
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene: RND3

Interactor 2: ANK3 (Q12955)
Ankyrin-3 (ANK-3) (Ankyrin-G)
Gene: ANK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras, Ank_4~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 244 Hs			1 4377
+	Hs
		915638 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		ANK3_HUMAN (1-4377): 0: 1944: 100.00
+	Hs
		893947 CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00		ANK3_HUMAN (1-4377): 0: 1944: 100.00
+	Hs
		925238 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		ANK3_HUMAN (1-4377): 0: 1944: 100.00
+	Hs
		900423 RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27		ANK3_HUMAN (1-4377): 0: 1944: 100.00
+	Hs
		950953 RHOG_HUMAN (23-208): 1.85e-74: 226: 42.47		ANK3_HUMAN (1-4377): 0: 1944: 100.00
+	Hs
		120412 RHOD_HUMAN (25-211): 1.61e-54: 176: 41.18		ANK3_HUMAN (1-4377): 0: 1944: 100.00
+	Hs
		1021465 RHOF_HUMAN (25-212): 1.18e-52: 171: 45.21		ANK3_HUMAN (1-4377): 0: 1944: 100.00
+	Hs
		1335390 RHOF_HUMAN (25-212): 1.18e-52: 171: 45.21		ANR50_HUMAN (1-568): 0: 670: 32.41
+	Hs
		120691 RHOD_HUMAN (25-211): 1.61e-54: 176: 41.18		ANFY1_HUMAN (270-925): 8.88e-121: 417: 18.16
+	Hs
		1335366 RHOF_HUMAN (25-212): 1.18e-52: 171: 45.21		ANFY1_HUMAN (270-925): 8.88e-121: 417: 18.16
+	Hs
		925204 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		ANK2_HUMAN (3012-4350): 1.52e-22: 110: 9.15