HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: KC1G3 (Q9Y6M4)
Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)
Gene: CSNK1G3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 447
+	Hs
		925773 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		436599 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		951505 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		894641 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		545731 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		892707 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		916109 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		120742 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		821977 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		KC1A_HUMAN (28-364): 3.67e-130: 381: 50.59
+	Hs
		681775 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		AKT1_HUMAN (4-386): 2.58e-122: 366: 19.74
+	Hs
		568611 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		KAPCA_HUMAN (6-370): 6.92e-123: 363: 19.95
+	Hs
		821973 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		KC1A_HUMAN (28-364): 3.67e-130: 381: 50.59
+	Hs
		568619 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		KAPCA_HUMAN (6-370): 6.92e-123: 363: 19.95
+	Hs
		436148 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		KAPCA_HUMAN (6-370): 6.92e-123: 363: 19.95
+	Hs
		568605 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		KAPCA_HUMAN (6-370): 6.92e-123: 363: 19.95
+	Hs
		545209 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		KAPCB_HUMAN (2-367): 3.04e-122: 361: 20.43
+	Hs
		623871 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		KPCL_HUMAN (3-384): 2.51e-120: 367: 15.72